Pro-Medrol 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 1,000.00

Medicine Details

Title

  • Pro-Medrol IM/IV 500mg Powder for Injection
  • Methylprednisolone Sodium Succinate

Categories

  • Medicine
  • Pharmaceutical

Description

  • Pro-Medrol IM/IV is a glucocorticoid used for various conditions including endocrine disorders, rheumatic disorders, collagen diseases, dermatological diseases, allergic states, ophthalmic diseases, gastrointestinal diseases, respiratory diseases, hematologic disorders, neoplastic diseases, edematous states, and more.
  • It is administered by IM or IV injection and is rapidly absorbed when given intramuscularly.

Color Options

  • White powder for injection

Functions

  • Anti-inflammatory effects
  • Replacement therapy in adrenocortical deficiency states
  • Potent effects in disorders of many organ systems
  • Exerts suppressive effect on immune response

Dosage & Administration

  • May be administered by IM or IV injection
  • High dose therapy recommended for certain conditions
  • Dosage must be decreased or discontinued gradually after prolonged therapy

Interaction

  • May interact with aminoglutethimide, amphotericin B, macrolide antibiotics, anticholinesterases, anticoagulants, antidiabetics, antitubercular drugs, cyclosporine, digitalis glycosides, estrogens, ketoconazole, NSAIDs, and vaccines

Contraindications

  • Contradicted in systemic fungal infections and known hypersensitivity to the product and its constituents
  • Contraindicated for intrathecal administration
  • Intramuscular corticosteroid preparations are contraindicated for idiopathic thrombocytopenic purpura

Side Effects

  • Fluid and electrolyte disturbances
  • Musculoskeletal issues
  • Gastrointestinal problems
  • Dermatologic complications
  • Neurological effects
  • Endocrine manifestations
  • Ophthalmic adverse reactions
  • Other adverse reactions

Pregnancy & Lactation

  • Corticosteroids may be teratogenic in many species
  • Should be used during pregnancy only if potential benefit justifies the potential risk to the fetus
  • Systemically administered corticosteroids may appear in human milk and could suppress growth in infants

Precautions & Warnings

  • Sensitive to heat
  • Lowest possible dose should be used
  • Complications are dependent on the size of the dose and duration of treatment
  • Discontinuation of corticosteroids may result in clinical improvement

Special Populations

  • Pediatric use may lead to growth effects
  • Geriatric use may differ from younger subjects in response and dose selection

Overdose Effects

  • Treatment is by supportive and symptomatic therapy
  • Chronic overdosage may require temporary dose reduction or alternate day treatment

Therapeutic Class

  • Glucocorticoids

Reconstitution

  • Directions for reconstitution of the powder for injection

Storage Conditions

  • Protect from light
  • Store at controlled room temperature 20°C to 25°C
  • Use solution within 48 hours after mixing

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