Solu-Medrol 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 1,947.00

Medicine Details

Category Details
Generic Methylprednisolone sodium succinate
Company Pfizer
Also available as
Solu medrol 1 gm injection Solu medrol 40 mg injection Solu medrol 125 mg injection

Title

  • Solu-Medrol IM/IV

Categories

  • Medicine
  • Healthcare
  • Pharmaceutical

Description

  • Methylprednisolone for Injection and Infusion

Indications

  • Endocrine disorder management
  • Rheumatic disorder treatment
  • Collagen disease therapy
  • Dermatological disease control
  • Allergic states management
  • Ophthalmic disease treatment
  • Gastrointestinal disease support
  • Respiratory disease management
  • Hematologic disorder therapy
  • Neoplastic disease palliation
  • Edematous state induction
  • Tuberculous meningitis management
  • Trichinosis management

Pharmacology

  • Glucocorticoid replacement therapy
  • Potent anti-inflammatory effects
  • Salt-retaining properties
  • Effects evident within one hour
  • Excretion within 12 hours
  • Influence on metabolic and electrolyte balance
  • Suppressive effect on the immune response

Dosage & Administration

  • Administered by IM or IV
  • High dose therapy recommendation
  • Initial dosage 10 to 40 mg
  • Dosing variation for pediatric patients
  • Short-term management with larger doses
  • Gradual decrease or discontinuation of dosage
  • Routine laboratory studies during prolonged therapy

Interaction

  • Interaction with Aminoglutethimide
  • Amphotericin B and potassium-depleting agents interaction
  • Macrolide antibiotics effects
  • Anticholinesterases impact
  • Anticoagulants and oral antidiabetics interaction
  • Antitubercular drugs effect
  • Cholestyramine influence
  • Cyclosporine concurrent use impact
  • Digitalis glycosides interaction
  • Estrogens and hepatic enzyme inhibitors effects
  • Ketoconazole impact
  • Nonsteroidal anti-inflammatory agents influence
  • Skin tests and vaccines effects

Contraindications

  • Systemic fungal infections
  • Hypersensitivity to the product
  • Intrathecal administration
  • Intramuscular corticosteroid contraindications

Side Effects

  • Fluid and Electrolyte Disturbances
  • Musculoskeletal effects
  • Gastrointestinal adverse reactions
  • Dermatologic impact
  • Neurological symptoms
  • Endocrine manifestations
  • Ophthalmic reactions
  • Other potential effects

Pregnancy & Lactation

  • Teratogenic potential during pregnancy
  • Use only if potential benefit justifies risk
  • Potential adverse effects on nursing infants

Precautions & Warnings

  • Sensitivity to heat
  • Use of lowest possible dose
  • Gradual reduction in dosage
  • Complications dependent on dose and duration
  • Risks and benefits assessment for each case
  • Clinical improvement upon discontinuation

Use in Special Populations

  • Adverse effects in pediatric patients
  • Growth effects of corticosteroids in pediatric patients
  • Monitoring and dose titration for pediatric use
  • Geriatric use considerations

Overdose Effects

  • Supportive and symptomatic therapy for acute overdose
  • Reduction of corticosteroid dosage for chronic overdose

Therapeutic Class

  • Glucocorticoids

Reconstitution

  • Directions for reconstitution
  • Use of Water for Injection BP
  • Agitation to dissolve the powder
  • Needle insertion and dose withdrawal

Storage Conditions

  • Protection from light
  • Controlled room temperature storage
  • Use within 48 hours after mixing

Related Brands