Solupred 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone sodium succinate |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Endocrine disorder
- Rheumatic disorder
- Collagen disease
- Dermatological disease
- Allergic states
- Ophthalmic disease
- Gastrointestinal disease
- Respiratory disease
- Hematologic disorder
- Neoplastic disease
- Edematous state
- Tuberculous meningitis
- Trichinosis
Pharmacology
- Naturally occurring glucocorticoid
- Potent anti-inflammatory effects
- Salt-retaining properties
- Excretion in 12 hours
- Influence on carbohydrate, protein, fat and purine metabolism
- Suppressive effect on the immune response
Dosage & Administration
- Administered by IM or IV
- High dose therapy
- Intravenous infusion over 30 minutes
- Dosage variations in pediatric patients
- Treatment of acute exacerbations of multiple sclerosis
Interaction
- Aminoglutethimide
- Amphotericin B injection
- Macrolide antibiotics
- Anticholinesterases
- Anticoagulants
- Antidiabetics
- Antitubercular drugs
- Cholestyramine
- Cyclosporine
- Digitalis glycosides
- Estrogens
- Hepatic Enzyme Inhibitors
- Ketoconazole
- Nonsteroidal anti-inflammatory agents
- Skin tests
- Vaccines
Contraindications
- Systemic fungal infections
- Hypersensitivity to the product
- Intrathecal administration
- Idiopathic thrombocytopenic purpura
Side Effects
- Sodium retention
- Muscle weakness
- Peptic ulcer
- Impaired wound healing
- Increased intracranial pressure
- Cushingoid state
- Posterior subcapsular cataracts
- Negative nitrogen balance
Pregnancy & Lactation
- Teratogenic in many species
- Potential risk to the fetus
- Suppression of growth in nursing infants
Precautions & Warnings
- Sensitive to heat
- Use of lowest possible dose
- Gradual reduction in dosage
- Complications dependent on dose and duration of treatment
Use in Special Populations
- Adverse effects in pediatric patients
- Careful observation in pediatric patients
- Decrease in growth velocity
- Cautious dose selection for geriatric use
Overdose Effects
- Supportive and symptomatic therapy
- Reduction of corticosteroid dosage
Therapeutic Class
- Glucocorticoids
Reconstitution
- Directions for reconstitution
- Protection from light
- Use within 48 hours after mixing
Storage Conditions
- Protect from light
- Store at controlled room temperature
- 48-hour use limit after mixing