Melpred 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone sodium succinate |
| Company | Pharmasia limited |
| Also available as |
Title
- Melpred IM/IV
Categories
- Medicine
- Glucocorticoids
Dimensions
- N/A
Color Options
- N/A
Functions
- Anti-inflammatory
- Replacement therapy for adrenocortical deficiency states
- Immunosuppressant
- Inducing diuresis
- Palliative management of leukemias and lymphoma
- Treatment of acute exacerbations of multiple sclerosis
Materials
- Methylprednisolone
- Sodium Succinate
Technical Specifications
- Potent anti-inflammatory effects
- Excretion of administered dose within 12 hours
- Rapid absorption when administered intramuscularly
- Exerts suppressive effect on the immune response
Design Elements
- Sterile Powder for Injection
Usability Features
- Indicated in various conditions such as endocrine disorder, rheumatic disorder, collagen disease, dermatological disease, allergic states, ophthalmic disease, gastrointestinal disease, respiratory disease, hematologic disorder, neoplastic disease, edematous state, and miscellaneous diseases
Dosage and Administration
- May be administered by IM or IV
- High dose therapy involves 30 mg/kg administered intravenously over at least 30 minutes
- Initial dose varies from 10 to 40 mg depending on the clinical problem being treated
Interaction
- Aminoglutethimide may lead to a loss of corticosteroid-induced adrenal suppression
- Macrolide antibiotics may cause a significant decrease in corticosteroid clearance
- Anticoagulants, oral: coadministration with corticosteroids may inhibit response to warfarin
Contraindications
- Systemic fungal infections
- Known hypersensitivity to the product and its constituents
- Intrathecal administration
- Intramuscular corticosteroid preparations for idiopathic thrombocytopenic purpura
Side Effects
- Fluid and electrolyte disturbances
- Musculoskeletal problems
- Gastrointestinal issues
- Dermatologic complications
- Neurological symptoms
- Endocrine-related effects
- Ophthalmic concerns
Pregnancy & Lactation
- Corticosteroids have been shown to be teratogenic in many species
- Infants born to mothers who received corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism
Precautions & Warnings
- Sensitive to heat
- Lowest possible dose should be used
- Complications of treatment are dependent on the size of the dose and the duration of treatment
Use in Special Populations
- Adverse effects in pediatric patients similar to adults
- Pediatric patients should be titrated to the lowest effective dose
- Dosing for the elderly should be cautious
Overdose Effects
- Supportive and symptomatic therapy for acute overdose
- For chronic overdose, temporary reduction of dosage may be required
Therapeutic Class
- Glucocorticoids
Reconstitution
- Remove protective plastic flip-off seal
- Cleansing stopper with a suitable germicide
- Aseptically adding Water for Injection BP into the vial
- Agitating to dissolve the powder content
- Using the solution within 48 hours after mixing
Storage Conditions
- Protect from light
- Store at controlled room temperature 20° to 25°C