Melpred 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 600.00

Medicine Details

Category Details
Generic Methylprednisolone sodium succinate
Company Pharmasia limited
Also available as
Melpred 1 gm injection

Indications

  • Endocrine disorder
  • Rheumatic disorder
  • Collagen disease
  • Dermatological disease
  • Allergic states
  • Ophthalmic disease
  • Gastrointestinal disease
  • Respiratory disease
  • Hematologic disorder
  • Neoplastic disease
  • Edematous state
  • Miscellaneous

Pharmacology

  • Naturally occurring glucocorticoid
  • Salt-retaining properties
  • Potent anti-inflammatory effects
  • Excretion within 12 hours
  • Influences metabolism and electrolyte balance
  • Suppressive effect on the immune response

Dosage & Administration

  • IM or IV administration
  • High dose therapy
  • Initial dosage variation
  • Dose reduction or discontinuation
  • Pediatric dosage variation
  • Specific recommendations for multiple sclerosis

Interaction

  • Aminoglutethimide
  • Amphotericin B interaction
  • Macrolide antibiotics effect
  • Anticholinesterases interaction
  • Anticoagulants interaction
  • Antidiabetics interaction
  • Antitubercular drugs interaction
  • Effect on skin tests and vaccines

Contraindications

  • Systemic fungal infections
  • Intrathecal administration
  • Idiopathic thrombocytopenic purpura

Side Effects

  • Fluid and Electrolyte Disturbances
  • Musculoskeletal effects
  • Gastrointestinal effects
  • Dermatologic effects
  • Neurological effects
  • Endocrine effects
  • Ophthalmic effects
  • Other potential adverse reactions

Pregnancy & Lactation

  • Teratogenic potential
  • Potential effects on nursing infants

Precautions & Warnings

  • Sensitivity to heat
  • Use of lowest possible dose
  • Gradual reduction in dosage
  • Risk/benefit decision for dose and duration
  • Clinical improvement upon discontinuation

Use in Special Populations

  • Pediatric Use
  • Geriatric Use

Overdose Effects

  • Supportive and symptomatic therapy
  • Chronic overdose management

Therapeutic Class

  • Glucocorticoids

Reconstitution

  • Directions for reconstitution

Storage Conditions

  • Protection from light
  • Controlled room temperature storage
  • Limited solution use within 48 hours

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