Mepcort 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone sodium succinate |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Title
- Mepcort IM/IV
Categories
- Medicine
- Pharmaceutical
Description
- Methylprednisolone Sodium Succinate for Injection, USP
Indications
- Endocrine disorder
- Rheumatic disorder
- Collagen disease
- Dermatological disease
- Allergic states
- Ophthalmic disease
- Gastrointestinal disease
- Respiratory disease
- Hematologic disorder
- Neoplastic disease
- Edematous state
- Miscellaneous
Pharmacology
- Potent anti-inflammatory effects
- Salt-retaining properties
- Excretion within 12 hours
- Influences various metabolic processes
- Suppressive effect on the immune response
Dosage & Administration
- Administered by IM or IV
- High dose therapy
- Dose varies based on clinical problem
- Decrease or discontinue dosage gradually
- Different initial dose for pediatric patients
- Treatment of acute exacerbations of multiple sclerosis
Interactions
- Aminoglutethimide
- Amphotericin B injection and potassium-depleting agents
- Macrolide antibiotics
- Anticholinesterases
- Anticoagulants, oral
- Antidiabetics
- Antitubercular drugs
- Cholestyramine
- Cyclosporine
- Digitalis glycosides
- Estrogens, including oral contraceptives
- Hepatic Enzyme Inhibitors
- Ketoconazole
- Nonsteroidal anti-inflammatory agents (NSAIDs)
- Skin tests
- Vaccines
Contraindications
- Systemic fungal infections
- Known hypersensitivity to the product
- Intrathecal administration
- Idiopathic thrombocytopenic purpura
Side Effects
- Fluid and Electrolyte Disturbances
- Musculoskeletal effects
- Gastrointestinal effects
- Dermatologic effects
- Neurological effects
- Endocrine effects
- Ophthalmic effects
- Other effects
- Additional adverse reactions related to parenteral corticosteroid therapy
Pregnancy & Lactation
- Teratogenic potential during pregnancy
- Corticosteroids in human milk
- Potential risk to the fetus
- Adverse effects in nursing infants
Precautions & Warnings
- Sensitive to heat
- Lowest possible dose should be used
- Reduction in dosage should be gradual
- Discontinuation may result in clinical improvement
Use in Special Populations
- Adverse effects in pediatric patients
- Monitoring of growth velocity
- Considerations for geriatric use
Overdose Effects
- Treatment with supportive and symptomatic therapy
- Reduction of corticosteroid dosage for chronic overdosage
Therapeutic Class
- Glucocorticoids
Reconstitution
- Directions for reconstitution
Storage Conditions
- Protect from light
- Store at controlled room temperature 20° to 25°C
- Use solution within 48 hours after mixing