Mepcort 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 600.00

Medicine Details

Category	Details
Generic	Methylprednisolone sodium succinate
Company	Globe pharmaceuticals ltd
Also available as	Mepcort 1 gm injection

Indications

Endocrine disorder
Rheumatic disorder
Collagen disease
Dermatological disease
Allergic states
Ophthalmic disease
Gastrointestinal disease
Respiratory disease
Hematologic disorder
Neoplastic disease
Edematous state
Tuberculous meningitis
Trichinosis

Pharmacology

Naturally occurring glucocorticoid
Salt-retaining properties
Potent anti-inflammatory effects
Rapid absorption
Excretion within 12 hours
Influence on carbohydrate, protein, and fat metabolism
Suppressive effect on the immune response

Dosage & Administration

Administered by IM or IV
High dose therapy
Variation in initial dosage
Dosage reduction or discontinuation
Pediatric dosage considerations
Treatment of acute exacerbations of multiple sclerosis

Interaction

Aminoglutethimide
Amphotericin B injection and potassium-depleting agents
Macrolide antibiotics
Anticholinesterases
Anticoagulants, oral
Antidiabetics
Antitubercular drugs
Cholestyramine
Cyclosporine
Digitalis glycosides
Estrogens
Hepatic Enzyme Inhibitors
Ketoconazole
Nonsteroidal anti-inflammatory agents (NSAIDs)
Skin tests
Vaccines

Contraindications

Systemic fungal infections
Hypersensitivity to the product and its constituents
Intrathecal administration
Idiopathic thrombocytopenic purpura

Side Effects

Fluid and electrolyte disturbances
Musculoskeletal effects
Gastrointestinal complications
Dermatologic manifestations
Neurological impact
Endocrine-related issues
Ophthalmic implications
Other adverse reactions
Pediatric and geriatric considerations

Pregnancy & Lactation

Teratogenic potential
No adequate and well-controlled studies
Potential effects on nursing infants
Risk/benefit assessment

Precautions & Warnings

Sensitivity to heat
Gradual dosage reduction
Complications dependent on dose and duration of treatment
Importance of gradual discontinuation

Use in Special Populations

Adverse effects in pediatric patients
Decrease in growth velocity
Observational considerations for pediatric patients
Geriatric use and response differences

Overdose Effects

Supportive and symptomatic therapy
Chronic overdosage management

Therapeutic Class

Glucocorticoids

Reconstitution

Directions for reconstitution
Protective plastic flip-of seal removal
Cleansing of stopper
Aseptic addition of Water for Injection BP
Agitation to effect solution
Needle insertion and dose withdrawal

Storage Conditions

Protection from light
Controlled room temperature storage
48-hour use timeframe for solution

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