Tibo 2.5 mg (Tablet)
Unit Price: ৳ 20.08 (3 x 10: ৳ 602.40)
Strip Price: ৳ 200.80
Medicine Details
| Category | Details |
|---|---|
| Generic | Tibolone |
| Company | Popular pharmaceuticals ltd |
Indications
- Treatment of symptoms resulting from natural or surgical menopause in postmenopausal women
- Prevention of osteoporosis in women at high risk of fractures post-menopause
Pharmacology
- Estrogenic, androgenic, and progestagenic properties
- Rapid metabolism into three active compounds
- Estrogenic effects on vagina, bone, and thermoregulatory centers in the brain
- Improvement of vaginal dryness and atrophy
- Effects on mood and libido
Dosage & Administration
- One tablet per day (2.5 mg daily)
- Swallow with water or other drink
- Commence treatment 12 months after last natural bleed for natural menopause
- Immediate commencement for surgical menopause
- Starting from sequential or continuous combined HRT preparation
- Guidelines for missed dose
Interaction
- Potential interactions with enzyme-inducing compounds
- Enhanced effect on anticoagulants
Contraindications
- Pregnancy and lactation
- Hormone-dependent tumors
- Cardiovascular or cerebrovascular disorders
- Active deep vein thrombosis
- Thromboembolic disorders
- Vaginal bleeding of unknown etiology
- Severe liver disorders
Side Effects
- Vaginal bleeding or spotting
- Headache and migraine
- Oedema
- Dizziness
- Pruritus
- Increase in body weight
- Nausea
- Abdominal pain
- Rash
- Depression
Pregnancy & Lactation
- Contraindicated during pregnancy
- Immediate withdrawal if pregnancy occurs during medication
- No clinical data on exposed pregnancies
Precautions & Warnings
- Renal dysfunction
- History of liver disease
- Epilepsy
- Migraine
- Hypercholesterolemia
- Impaired carbohydrate metabolism
- Diabetes mellitus
- Cholestatic jaundice
Overdose Effects
- Low acute toxicity in animals
- Nausea, vomiting, and withdrawal bleeding in females
- Symptomatic treatment
Therapeutic Class
- Drugs for menopausal symptoms: Hormone Replacement Therapy
Storage Conditions
- Cool and dry place
- Protect from light
- Keep out of the reach of children