Ubilon 2.5 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Tibolone
Company Incepta pharmaceuticals ltd

Indications

  • Treatment of symptoms resulting from natural or surgical menopause in postmenopausal women
  • Prevention of osteoporosis in postmenopausal women at high risk of fractures

Pharmacology

  • Synthetic steroid with estrogenic, androgenic, and progestagenic properties
  • Rapid metabolism into three compounds contributing to pharmacological effects
  • Estrogenic effects on the vagina, bone, and thermoregulatory centers in the brain
  • Improvement of vaginal dryness, vaginal atrophy, mood, and libido

Dosage & Administration

  • One tablet per day (2.5 mg daily)
  • Swallowed with water or other drink at the same time each day
  • Optimal results obtained when therapy is continued for at least 3 months
  • Specific starting dosage guidelines for different menopausal situations
  • Instructions for missed dose

Interaction

  • No reported examples of interactions with other medicines in clinical practice
  • Potential interactions with enzyme-inducing compounds and anticoagulants

Contraindications

  • Pregnancy and lactation
  • Known or suspected hormone-dependent tumors
  • Cardiovascular or cerebrovascular disorders
  • Active deep vein thrombosis and thromboembolic disorders
  • Vaginal bleeding of unknown etiology
  • Severe liver disorders

Side Effects

  • Occasional vaginal bleeding or spotting
  • Headache and migraine
  • Oedema, dizziness, pruritus
  • Increase in body weight, nausea, abdominal pain
  • Rash and depression

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Immediate withdrawal if pregnancy occurs during medication
  • No clinical data on exposed pregnancies available
  • Contraindicated in lactating women

Precautions & Warnings

  • Patients with renal dysfunction, history of liver disease
  • Epilepsy, migraine, hypercholesterolemia
  • Impaired carbohydrate metabolism, diabetes mellitus
  • Cholestatic jaundice

Overdose Effects

  • Acute toxicity in animals is very low
  • Toxic symptoms not expected with simultaneous intake of several tablets
  • Possible symptoms of nausea, vomiting, and withdrawal bleeding in females
  • Symptomatic treatment if necessary

Therapeutic Class

  • Drugs for menopausal symptoms: Hormone replacement therapy

Storage Conditions

  • Keep in a cool & dry place
  • Protect from light
  • Keep out of the reach of children

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