Tibilon 2.5 mg (Tablet)
Unit Price: ৳ 21.56 (1 x 28: ৳ 603.68)
Strip Price: ৳ 603.68
Medicine Details
| Category | Details |
|---|---|
| Generic | Tibolone |
| Company | Beximco pharmaceuticals ltd |
Indications
- Treatment of symptoms resulting from natural or surgical menopause
- Prevention of osteoporosis in postmenopausal women at high risk of fractures
Pharmacology
- Synthetic steroid with estrogenic, androgenic, and progestagenic properties
- Rapid metabolism into three compounds contributing to pharmacological effects
- Estrogenic effects on vagina, bone, and thermoregulatory centers in the brain
- Improves vaginal dryness, vaginal atrophy, mood, and libido
Dosage & Administration
- One tablet per day (2.5 mg daily)
- Swallow with water or other drink at the same time each day
- Optimal results after at least 3 months of therapy
- Commencement after natural menopause or surgical menopause
- Instructions for switching from other hormone replacement therapy (HRT) preparations
- Guidance for missed dose
Interaction
- No reported interactions with other medicines in clinical practice
- Considerations for potential interactions with enzyme-inducing compounds and anticoagulants
Contraindications
- Pregnancy and lactation
- Known or suspected hormone-dependent tumors
- Cardiovascular or cerebrovascular disorders
- Active deep vein thrombosis, thromboembolic disorders
- Vaginal bleeding of unknown etiology
- Severe liver disorders
Side Effects
- Occasional vaginal bleeding or spotting
- Adverse effects such as headache, migraine, oedema, dizziness, pruritus, weight gain, nausea, abdominal pain, rash, and depression
Pregnancy & Lactation
- Contraindicated during pregnancy
- Immediate withdrawal if pregnancy occurs during medication
- No available clinical data on exposed pregnancies
- Contraindicated in lactating women
Precautions & Warnings
- In patients with renal dysfunction, history of liver disease, epilepsy, migraine, hypercholesterolemia, impaired carbohydrate metabolism, diabetes mellitus, and cholestatic jaundice
Overdose Effects
- Very low acute toxicity in animals
- Symptoms like nausea, vomiting, and withdrawal bleeding in females
- Symptomatic treatment if necessary
Therapeutic Class
- Drugs for menopausal symptoms: Hormone replacement therapy
Storage Conditions
- Keep in a cool & dry place
- Protect from light
- Keep out of the reach of children