Tibone 2.5 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Tibolone
Company Techno drugs ltd

Indications

  • Treatment of symptoms resulting from natural or surgical menopause in post menopausal women
  • Prevention of osteoporosis in women at high risk of fractures

Pharmacology

  • Estrogenic, androgenic, and progestagenic properties
  • Contains three metabolites with varying activities
  • Substitutes for loss of estrogen production in postmenopausal women
  • Alleviates menopausal symptoms
  • Prevents bone loss following menopause or ovariectomy
  • Improves vaginal dryness and atrophy
  • Affects mood and libido

Dosage & Administration

  • One tablet per day (2.5 mg daily)
  • Should be swallowed with water at the same time each day
  • Improvement of symptoms generally occurs within a few weeks
  • Optimal results after at least 3 months of therapy
  • Commencement timing for natural and surgical menopause
  • Instructions for switching from other hormone replacement therapy
  • Guidance on missed doses

Interaction

  • No reported interactions with other medicines
  • Theoretical potential interactions with enzyme-inducing compounds
  • Possible enhancement of anticoagulant effect

Contraindications

  • Pregnancy and lactation
  • Hormone-dependent tumours
  • Cardiovascular or cerebrovascular disorders
  • Active deep vein thrombosis
  • Thromboembolic disorders
  • Vaginal bleeding of unknown etiology
  • Severe liver disorders

Side Effects

  • Vaginal bleeding or spotting
  • Headache and migraine
  • Oedema
  • Dizziness
  • Pruritus
  • Increase in body weight
  • Nausea
  • Abdominal pain
  • Rash
  • Depression

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Treatment withdrawal if pregnancy occurs
  • No available clinical data on exposed pregnancies
  • Contraindicated in lactating women

Precautions & Warnings

  • Patients with renal dysfunction
  • Patients with history of liver disease
  • Patients with epilepsy
  • Patients with migraine
  • Patients with hypercholesterolemia
  • Patients with impaired carbohydrate metabolism
  • Patients with diabetes mellitus
  • Patients with cholestatic jaundice

Overdose Effects

  • Acute toxicity is very low in animals
  • Toxic symptoms not expected if several tablets are taken simultaneously
  • Possible symptoms: nausea, vomiting, withdrawal bleeding in females
  • Symptomatic treatment can be given if necessary

Therapeutic Class

  • Drugs for menopausal symptoms
  • Hormone replacement therapy

Storage Conditions

  • Keep in a cool & dry place
  • Protect from light
  • Keep out of the reach of children

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