Tibonor 2.5 mg (Tablet)
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tibolone |
| Company | Eskayef pharmaceuticals ltd |
Indications
- Treatment of symptoms resulting from natural or surgical menopause in post menopausal women
- Prevention of osteoporosis in menopausal women at high risk of fractures
Pharmacology
- Estrogenic, androgenic, and progestagenic properties
- Rapid metabolism into three compounds
- Estrogenic effects on vagina, bone, and brain thermoregulatory centers
- Improvement of vaginal dryness and atrophy
- Effects on mood and libido
Dosage & Administration
- One Tibolone tablet per day (2.5 mg daily)
- Swallowed with water or other drink
- Commence treatment 12 months after last natural bleed for natural menopause
- Immediate commencement for surgical menopause
- Guidelines for switching from sequential or continuous HRT preparation
- Instructions for missed dose
Interaction
- No reported interactions with other medicines in clinical practice
- Potential interactions with enzyme-inducing compounds and anticoagulants
Contraindications
- Pregnancy and lactation
- Known or suspected hormone-dependent tumors
- Cardiovascular or cerebrovascular disorders
- Active deep vein thrombosis
- Thromboembolic disorders
- Vaginal bleeding of unknown etiology
- Severe liver disorders
Side Effects
- Vaginal bleeding or spotting
- Headache and migraine
- Oedema
- Dizziness
- Pruritus
- Increase in body weight
- Nausea
- Abdominal pain
- Rash
- Depression
Pregnancy & Lactation
- Contraindicated during pregnancy
- Immediate withdrawal if pregnancy occurs during medication
- No clinical data available on exposed pregnancies
- Contraindicated in lactating women
Precautions & Warnings
- Renal dysfunction
- History of liver disease
- Epilepsy
- Migraine
- Hypercholesterolemia
- Impaired carbohydrate metabolism
- Diabetes mellitus
- Cholestatic jaundice
Overdose Effects
- Low acute toxicity
- Possible symptoms include nausea, vomiting, withdrawal bleeding
- Symptomatic treatment if necessary
Therapeutic Class
- Drugs for menopausal symptoms: Hormone replacement therapy
Storage Conditions
- Cool & dry place
- Protect from light
- Keep out of the reach of children