Tivion 2.5 mg (Tablet)

Unit Price: ৳ 20.06 (3 x 10: ৳ 601.80)
Strip Price: ৳ 200.60

Medicine Details

Category Details
Generic Tibolone
Company Aci limited

Indications

  • Treatment of symptoms resulting from natural or surgical menopause in postmenopausal women
  • Prevention of osteoporosis in postmenopausal women at high risk of fractures

Pharmacology

  • Synthetic steroid with estrogenic, androgenic, and progestagenic properties
  • Rapid metabolism into three compounds with different activities
  • Substitutes for loss of estrogen production
  • Alleviates menopausal symptoms
  • Prevents bone loss after menopause or ovariectomy
  • Effects on vaginal dryness, vaginal atrophy, mood, and libido

Dosage & Administration

  • One tablet per day (2.5 mg daily)
  • Swallowed with water or other drink
  • Optimal results after at least 3 months of therapy
  • Specific starting guidelines for natural and surgical menopause
  • Instructions for switching from different hormone replacement therapy preparations
  • Guidance for missed dose

Interaction

  • No reported interactions with other medicines in clinical practice
  • Theoretical interactions with enzyme-inducing compounds and anticoagulants

Contraindications

  • Pregnancy and lactation
  • Known or suspected hormone-dependent tumors
  • Cardiovascular or cerebrovascular disorders
  • Active deep vein thrombosis and thromboembolic disorders
  • Vaginal bleeding of unknown etiology
  • Severe liver disorders

Side Effects

  • Vaginal bleeding or spotting, especially in initial months
  • Headache and migraine
  • Oedema and dizziness
  • Pruritus and increase in body weight
  • Nausea and abdominal pain
  • Rash and depression

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Immediate withdrawal of treatment if pregnancy occurs
  • No available clinical data on exposed pregnancies
  • Contraindicated in lactating women

Precautions & Warnings

  • Patients with renal dysfunction
  • History of liver disease
  • Epilepsy and migraine
  • Hypercholesterolemia and impaired carbohydrate metabolism
  • Diabetes mellitus and cholestatic jaundice

Overdose Effects

  • Very low acute toxicity in animals
  • Symptoms of overdose include nausea, vomiting, and withdrawal bleeding
  • Symptomatic treatment in necessary cases

Therapeutic Class

  • Drugs for menopausal symptoms: Hormone replacement therapy

Storage Conditions

  • Cool and dry place
  • Protection from light
  • Keep out of the reach of children

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