Veagra 50 mg (Tablet)
Unit Price: ৳ 30.00 (1 x 4: ৳ 120.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sildenafil citrate |
| Company | Astra biopharmaceuticals ltd |
| Also available as |
Indications
- Treatment of erectile dysfunction in men
- Treatment of pulmonary arterial hypertension
Description
- Selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5)
- Requires sexual stimulation for effectiveness
Mechanism of Action
- Inhibition of PDE5 by increasing levels of cGMP
- Results in smooth muscle relaxation and inflow of blood into penile tissues
Pharmacokinetics and Metabolism
- Rapid absorption after oral administration
- Mean absolute bioavailability of 41%
- Eliminated predominantly by hepatic metabolism
Dosage & Administration
- Recommended initial dose of 50 mg
- May be taken 1 hour before sexual activity
- Maximum recommended dose of 100 mg
Interaction
- Metabolism mediated by cytochrome P450 isoforms
- Inhibitors of these isoenzymes may reduce clearance
- Inducers of these isoenzymes may increase clearance
Contraindications
- Hypersensitivity to any component of the medication
- Contraindicated in patients using organic nitrates
Side Effects
- Body as a whole
- Cardiovascular
- Digestive
- Hemic and Lymphatic
- Metabolic and Nutritional
- Musculoskeletal
- Nervous
- Respiratory
- Skin and Appendages
- Special Senses
- Urogenital
- Cardiovascular and cerebrovascular
- Nervous
- Urogenital
- Special Senses
Pregnancy & Lactation
- Pregnancy category B
- No adequate and well-controlled studies in pregnant women
- Not indicated for use by women
Precautions & Warnings
- Evaluation of erectile dysfunction should include determination of potential underlying causes
- Caution advised when co-administered with alpha-blockers
- Considerations for patients stable on alpha-blocker therapy
- Potential cardiac risk of sexual activity in patients with preexisting cardiovascular disease
Overdose Effects
- Adverse events similar to lower doses but with increased incidence rates and severities
- Standard supportive measures should be adopted as required
- Renal dialysis not expected to accelerate clearance
Therapeutic Class
- Drugs for Erectile Dysfunction
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children