Silagra 50 mg (Tablet)
Unit Price: ৳ 30.00 (1 x 4: ৳ 120.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sildenafil citrate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of men with erectile dysfunction
- Treatment of pulmonary arterial hypertension
Description
- Selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5)
- Mechanism of smooth muscle relaxation
- Requires sexual stimulation for efficacy
Pharmacology
- MechanismOfAction: Release of nitric oxide
- Metabolism: Hepatic metabolism
- AbsorptionAndDistribution: Rapidly absorbed, affected by high-fat meal
- Excretion: Predominantly feces, lesser extent in urine
- SpecialPopulations: Reduced clearance in elderly volunteers
DosageAndAdministration
- Recommended dose of 50mg for erectile dysfunction
- Maximum recommended dose of 100mg
- Dosage factors associated with increased plasma levels
Interaction
- MetabolismMediatedByCYP: Inhibitors and inducers affecting clearance
- EffectOnOtherDrugs: Interactions with specific inhibitors and inducers
Contraindications
- Hypersensitivity to any component
- Concomitant use with nitrates
SideEffects
- Various body reactions
- Cardiovascular, digestive, hemic and lymphatic, metabolic and nutritional, musculoskeletal, nervous, respiratory, skin and appendages, special senses, urogenital
PregnancyAndLactation
Pregnancy category B, not indicated for use by women
PrecautionsAndWarnings
- Evaluation of underlying causes of erectile dysfunction
- Caution with alpha-blockers, systemic vasodilatory properties
- Potential cardiac risk with sexual activity
OverdoseEffects
Adverse events similar to lower doses, increased severity
TherapeuticClass
Drugs for Erectile Dysfunction
StorageConditions
Dry place, away from light and heat, keep out of the reach of children