Viax 50 mg (Tablet)

Unit Price: ৳ 30.00 (1 x 4: ৳ 120.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Sildenafil citrate
Company Opsonin pharma ltd
Also available as

Title

  • Viax
  • Sildenafil Citrate

Categories

  • Medicine
  • Pharmaceuticals
  • Healthcare

Description

  • Selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5)
  • Produces increased levels of cGMP in the corpus cavernosum upon sexual stimulation
  • Results in smooth muscle relaxation and increased blood flow into the penile tissues
  • Effective treatment for men with erectile dysfunction
  • Indicated in pulmonary arterial hypertension

Dosage & Administration

  • Recommended starting dose: 50 mg
  • May be taken 1 hour before sexual activity
  • May be increased to a maximum recommended dose of 100 mg or decreased to 25 mg based on effectiveness and toleration
  • Maximum recommended dosing frequency is once per day

Interaction

  • Metabolism is mediated by the cytochrome P450 (CYP) isoforms 3A4 and 2C9
  • Inhibitors of these isoenzymes may reduce clearance, while inducers may increase clearance
  • Potential interactions with CYP3A4 inhibitors, such as ketoconazole, itraconazole, erythromycin, saquinavir
  • Potential effects on plasma levels when co-administered with HIV protease inhibitors, alpha-blockers, and endothelin receptor antagonist bosentan

Contraindications

  • Hypersensitivity to any component of the medication
  • Use of organic nitrates, either regularly or intermittently

Side Effects

  • Body as a whole: face edema, photosensitivity reaction, shock, asthenia, pain
  • Cardiovascular: angina pectoris, AV block, migraine, syncope
  • Digestive: vomiting, glossitis, colitis, dysphagia
  • Hemic and Lymphatic: anemia, leukopenia
  • Metabolic and Nutritional: thirst, edema, gout, unstable diabetes
  • Musculoskeletal: arthritis, arthrosis, myalgia
  • Nervous: ataxia, hypertonia, neuralgia, neuropathy
  • Respiratory: asthma, dyspnea, laryngitis
  • Skin and Appendages: urticaria, herpes simplex, pruritus
  • Special Senses: sudden decrease or loss of hearing, mydriasis, conjunctivitis
  • Urogenital: cystitis, nocturia, urinary frequency, breast enlargement, urinary incontinence

Pregnancy & Lactation

  • Pregnancy category B
  • Not indicated for use by women
  • Animal studies show no evidence of teratogenicity or embryotoxicity

Precautions & Warnings

  • Caution advised when co-administered with alpha-blockers
  • Considerations for patients with hemodynamic instability, bleeding disorders, active peptic ulceration, anatomical deformation of the penis
  • Potential cardiac risk of sexual activity in patients with preexisting cardiovascular disease
  • Sensitivity to the actions of vasodilators including Viax in specific patient groups
  • Risk of prolonged erection greater than 4 hours and priapism
  • Unknown safety and efficacy in certain patient groups

Overdose Effects

  • Adverse events similar to lower doses, but with increased incidence rates and severities
  • Standard supportive measures should be adopted in cases of overdose
  • Renal dialysis is not expected to accelerate clearance

Therapeutic Class

  • Drugs for Erectile Dysfunction

Storage Conditions

  • Keep in a dry place, away from light and heat
  • Keep out of the reach of children

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