Minomal R 175 mg (Retard Tablet)
Unit Price: ৳ 1.23 (10 x 10: ৳ 123.00)
Strip Price: ৳ 12.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Aminophylline |
| Company | Pacific pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of bronchospasm associated with asthma
- Treatment of bronchospasm associated with emphysema
- Treatment of bronchospasm associated with chronic bronchitis
- Treatment of cardiac asthma
- Treatment of left ventricular or congestive cardiac failure
Pharmacology
- Combination of theophylline and ethylenediamine
- Ethylenediamine increases solubility of theophylline in water
- Theophylline relaxes bronchial smooth muscle
- Increase in intracellular cAMP through inhibition of phosphodiesterase
- Adenosine receptor antagonism
- Prostaglandin antagonism
- Effects on intracellular calcium
Dosage
- Oral administration
- Chronic bronchospasm dosing for adults
- Chronic bronchospasm dosing for children
- Intravenous administration
- Acute severe bronchospasm dosing for adults
- Acute severe bronchospasm dosing for children
- Elderly dose reduction may be necessary
- Dose reduction for hepatic impairment
Administration
- Tablets should be swallowed whole
- Tablets should not be chewed
Contraindications
- Hypersensitivity to xanthines or ethylenediamine
- Active peptic ulcer
Side Effects
- Gastric irritation
- Nausea
- Vomiting
- Diarrhea
- Hematemesis
- Epigastric pain
- Tremor
- Ventricular arrhythmias
- Seizures
- Reactivation of peptic ulcer
- Headache
- Irritability
- Restlessness
- Insomnia
- Twitching
- Convulsion
- Reflex hyperexcitability
- Palpitation
- Tachycardia
- Hypotension
- Circulatory failure
- Flushing
- Albuminuria
- Diuresis
- Hematuria
- Inappropriate ADH syndrome
Pregnancy & Lactation
- Use should be balanced against the risk of uncontrolled disease
Precautions & Warnings
- Use with caution in patients with peptic ulceration
- Use with caution in patients with hyperthyroidism
- Use with caution in patients with hypertension
- Use with caution in patients with cardiac arrhythmias or other cardiovascular disease
- Use with caution in patients with epilepsy
- Caution in heart failure patients
- Caution in patients with hepatic dysfunction
- Caution in patients with chronic alcoholism
- Caution in patients with acute febrile illness
- Caution in neonates and the elderly
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
- Respiratory stimulants
- Analeptics
- Theophylline & related drugs