Edysta 5 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Tadalafil |
Company | Unimed unihealth pharmaceuticals ltd |
Also available as |
Indications
- Erectile Dysfunction (ED)
- Benign Prostatic Hyperplasia (BPH)
- Both Erectile Dysfunction and signs and symptoms of Benign Prostatic Hyperplasia
Pharmacology
Selective phosphodiesterase type 5 (PDE5) inhibitor. Increases cGMP in smooth muscle cells, causing smooth muscle relaxation and increased blood flow into the corpus cavernosum, also affecting smooth muscles of the prostate and bladder wall to improve blood flow and urinary tract function.
Dosage & Administration
- Erectile Dysfunction: Recommended starting dose is 10 mg with a maximum dosing frequency of once daily, effective for up to 36 hours.
- Benign prostatic hyperplasia: Recommended dose is 5 mg taken at the same time every day.
- Combined Erectile Dysfunction and Benign prostatic hyperplasia: Recommended dose is 5 mg at the same time every day.
Interaction
May interact with Nitrates, Alpha adrenergic blockers, Antihypertensives, Alcohol, Antacids, Ketoconazole, Ritonavir, Erythromycin, Itraconazole, Grapefruit juice, other HIV protease inhibitors, Rifampin, Carbamazepine, Phenytoin, and Phenobarbital.
Contraindications
- Use of Nitrates
- Hypersensitivity reactions to Tadalafil
Side Effects
- Headache
- Dyspepsia
- Back pain
- Myalgia
- Nasal pharyngitis
- Nasal congestion
- Change in Color Vision
- Sudden vision loss
- Hearing loss
- Stevens-Johnson Syndrome
- Exfoliative dermatitis
- Angina
- Stroke
- Myocardial infarction
- Severe hypotension
- Tachycardia
Pregnancy & Lactation
Tadalafil has been assigned to pregnancy category B by the USFDA, recommended for use during pregnancy when benefit outweighs risk. Caution should be used when administering tadalafil to nursing women.
Precautions & Warnings
- Angina
- Renal impairment
- Hepatic impairment
- Bleeding concomitant with Nitrates
- Alpha Blockers
- Alcohol
- CYP3A4 Inhibitors
- Other PDE5 inhibitors
Therapeutic Class
Drugs for Erectile Dysfunction
Storage Conditions
Keep in a dry place, away from light and heat, out of the reach of children.