kTx 20 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Tadalafil |
| Company | Kemiko pharmaceuticals ltd |
| Also available as |
Indications
- Erectile Dysfunction (ED)
- Benign Prostatic Hyperplasia (BPH)
- Both Erectile Dysfunction and BPH
Pharmacology
Tadalafil is a PDE5 inhibitor that increases cGMP in smooth muscle cells, leading to smooth muscle relaxation and increased blood flow into the corpus cavernosum. It also relaxes smooth muscles in the prostate and bladder, improving voiding.
Dosage & Administration
- Erectile Dysfunction: Recommended starting dose is 10 mg, with a maximum frequency of once daily and effective for up to 36 hours.
- Benign Prostatic Hyperplasia: Recommended dose is 5 mg taken at the same time every day.
- Combined ED and BPH: Recommended dose is 5 mg at the same time every day.
Interaction
May interact with Nitrates, Alpha adrenergic blockers, Antihypertensives, Alcohol, Antacids, Ketoconazole, Ritonavir, Erythromycin, Itraconazole, Grapefruit juice, other HIV protease inhibitors, Rifampin, Carbamazepine, Phenytoin & Phenobarbital.
Contraindications
- Use of Nitrates
- Hypersensitivity reactions to Tadalafil
Side Effects
- Headache
- Dyspepsia
- Back pain
- Myalgia
- Nasal pharyngitis
- Nasal congestion
- Change in Color Vision
- Sudden vision loss
- Hearing loss
- Stevens-Johnson Syndrome
- Exfoliative dermatitis
- Angina
- Stroke
- Myocardial infarction
- Severe hypotension
- Tachycardia
Pregnancy & Lactation
Tadalafil is pregnancy category B by the USFDA, recommended for use during pregnancy when benefit outweighs risk. Caution should be used when administering to nursing women.
Precautions & Warnings
- Angina
- Renal impairment
- Hepatic impairment
- Bleeding concomitant with Nitrates
- Alpha Blockers
- Alcohol
- CYP3A4 Inhibitors
- Other PDE5 inhibitors
Therapeutic Class
Drugs for Erectile Dysfunction
Storage Conditions
Keep in a dry place, away from light and heat. Keep out of the reach of children.