Oracyn-K 250 mg (Tablet)

Unit Price: ৳ 2.80 (30 x 10: ৳ 840.00)

Strip Price: ৳ 28.00

Medicine Details

Category	Details
Generic	Phenoxymethyl penicillin penicillin v
Company	Synovia pharma plc
Also available as	Oracyn k 500 mg tablet Oracyn k 125 mg suspension

Title and Categories

Oracyn-K Tablets
Antibiotic
Phenoxymethyl Penicillin
Benzylpenicillin
Prescription Medicine
Infection Treatment
Phenoxymethylpenicillin Tablets

Dosage Form

Tablet

Packaging

Blister Pack
Bottle

Pack Sizes

10 tablets
20 tablets
30 tablets
50 tablets

Manufacturer

Pharmaceutical Company XYZ

Active Ingredient

Phenoxymethylpenicillin

Absorption

Absorbed from upper part of small intestine

Acid Stability

Acid-stable

Absorption Enhancement

Best absorbed as potassium salt

Administration Guidelines

Take with meals for maximum absorption, or one hour before or two hours after meals for best results

Dosage for Adults

250-500 mg every 6 hours

Dosage for Children

125-250 mg every 6 hours
125 mg/5 ml powder for suspension: 1-2 teaspoonful (5-10 ml) every 6 hours
250 mg/5 ml powder for suspension: ½-1 teaspoonful (2.5-5 ml) every 6 hours

Dosage for Infants

62.5-125 mg every 6 hours
125 mg/5 ml powder for suspension: ½-1 teaspoonful (2.5-5 ml) every 6 hours, or as prescribed by the physician

Best Time for Administration

Best taken on an empty stomach, preferably one hour before meals

Food Interaction

Concurrent intake of food reduces absorption rate

Drug Interactions

Increased levels of methotrexate in serum
Disturbed absorption of other orally administered drugs if diarrhea occurs
Attenuated activity if combined with bacteriostatic chemotherapeutics or antibiotics
Renal excretion inhibition when combined with probenecid
Elevated and prolonged serum levels when taken with indomethacin, phenylbutazone, salicylates or sulfinpyrazone
Transient reduction in plasma concentrations of oestrogens and gestagens when administered with penicillins
Reduced absorption after intestinal sterilization with aminoglycosides
Prolonged prothrombin time/INR when combined with oral anticoagulants

Precautions for Pregnancy & Lactation

Crosses placenta
May be used throughout pregnancy with appropriate indication
Passes into breast milk in small amounts
May be used during lactation, but may cause diarrhoea and yeast colonization in the infant

Contraindications

Hypersensitivity to penicillins or any of the excipients
Severe gastrointestinal disorders accompanied by vomiting and diarrhea

Side Effects

Hypersensitivity reactions involving the skin
Serious allergic reactions
Anaphylactic or anaphylactoid reactions
Skin rashes or inflammation of mucous membranes
Gastrointestinal disturbances
Pseudomembranous colitis
Changes in blood picture
Herxheimer's reaction
Drug-induced aseptic meningitis
Transient discolouration of the teeth
Proliferation of resistant microorganisms

Precautions & Warnings

Possibility of cross-allergy between cephalosporins and penicillins
Consider potassium content for patients with heart diseases or serious electrolyte disturbances
Regular check of patient's condition for resistance proliferation and secondary infection
Consider sugar content for patients with diabetes mellitus
No impairment to drive or operate machinery, but predisposition to encephalopathy risk should be noted

Overdose Effects

Low toxicity
No acute toxicity for single multiple therapeutic dose
Risk of encephalopathy in case of overdose or renal impairment
No special measures required for overdose other than discontinuation of medication
Elimination through haemodialysis possible