Penvik 250 mg (Tablet)

Unit Price: ৳ 2.80 (10 x 10: ৳ 280.00)
Strip Price: ৳ 28.00

Medicine Details

Category Details
Generic Phenoxymethyl penicillin penicillin v
Company Square pharmaceuticals plc
Also available as
Penvik ds 500 mg tablet Penvik forte 250 mg suspension

Indications

  • Mild to moderately severe bacterial infections treatment
  • Ear, nose, and throat infections treatment
  • Lower respiratory tract infections treatment
  • Skin infections treatment
  • Lymphadenitis and lymphangitis treatment
  • Prophylaxis of scarlet fever
  • Prevention of recurrences of rheumatic fever
  • Prophylaxis of infection after dental and oral surgical procedures
  • Combination therapy with another appropriate antibiotic

Pharmacology

  • Acid-stable
  • Absorption from the upper part of the small intestine
  • Best absorbed when given with meals
  • Convenient means of treating Gram-positive infections
  • Advantage over penicillin G in resistance to inactivation by gastric acid

Dosage

  • Determined according to the sensitivity of the causative micro-organism
  • Adjusted to the severity of the infection
  • Administered orally
  • Different dosage for adults, children, and infants

Administration

  • Best taken on an empty stomach
  • Tablets swallowed without chewing
  • Syrup bottle shaken vigorously before each use

Interaction

  • Reduced rate of absorption with concurrent food intake
  • Potential drug interactions with methotrexate, probenecid, and others
  • Possible interference with laboratory and diagnostic tests

Contraindications

  • Hypersensitivity to penicillins
  • Severe gastrointestinal disorders accompanied by vomiting and diarrhea

Side Effects

  • Hypersensitivity reactions involving the skin
  • Allergic reactions such as drug fever, vasculitis, and serum sickness
  • Anaphylactic or anaphylactoid reactions
  • Skin rashes or inflammation of mucous membranes
  • Gastrointestinal disturbances
  • Diarrhoea as a symptom of enterocolitis
  • Blood picture changes
  • Herxheimer's reaction during spirochaetal infections treatment
  • Transient discolouration of the teeth
  • Potential for antibiotic-induced resistant microorganism proliferation

Pregnancy & Lactation

  • Crosses the placenta
  • Passes into the breast milk in small amounts
  • Appropriate use during pregnancy and lactation

Precautions & Warnings

  • Possibility of cross-allergy between cephalosporins and penicillins
  • Consideration of the potassium content in patients with heart diseases or electrolyte disturbances
  • Predisposition to encephalopathy risk
  • Check patient's condition at regular intervals
  • Consideration for sugar content in patients with diabetes mellitus
  • No impairment of ability to drive or operate machinery
  • Precautions in case of adverse reactions such as encephalopathy

Overdose Effects

  • Low toxicity
  • Broad therapeutic range
  • Risk of encephalopathy in case of beta-lactam antibiotics administration
  • No special measures required other than discontinuation of medication
  • Possibility of elimination through haemodialysis

Therapeutic Class

  • Benzylpenicillin
  • Phenoxymethyl penicillin

Storage Conditions

  • Cool and dry storage
  • Protection from light

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