Penvik 250 mg (Tablet)
Unit Price: ৳ 2.80 (10 x 10: ৳ 280.00)
Strip Price: ৳ 28.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Phenoxymethyl penicillin penicillin v |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Mild to moderately severe bacterial infections treatment
- Ear, nose, and throat infections treatment
- Lower respiratory tract infections treatment
- Skin infections treatment
- Lymphadenitis and lymphangitis treatment
- Prophylaxis of scarlet fever
- Prevention of recurrences of rheumatic fever
- Prophylaxis of infection after dental and oral surgical procedures
- Combination therapy with another appropriate antibiotic
Pharmacology
- Acid-stable
- Absorption from the upper part of the small intestine
- Best absorbed when given with meals
- Convenient means of treating Gram-positive infections
- Advantage over penicillin G in resistance to inactivation by gastric acid
Dosage
- Determined according to the sensitivity of the causative micro-organism
- Adjusted to the severity of the infection
- Administered orally
- Different dosage for adults, children, and infants
Administration
- Best taken on an empty stomach
- Tablets swallowed without chewing
- Syrup bottle shaken vigorously before each use
Interaction
- Reduced rate of absorption with concurrent food intake
- Potential drug interactions with methotrexate, probenecid, and others
- Possible interference with laboratory and diagnostic tests
Contraindications
- Hypersensitivity to penicillins
- Severe gastrointestinal disorders accompanied by vomiting and diarrhea
Side Effects
- Hypersensitivity reactions involving the skin
- Allergic reactions such as drug fever, vasculitis, and serum sickness
- Anaphylactic or anaphylactoid reactions
- Skin rashes or inflammation of mucous membranes
- Gastrointestinal disturbances
- Diarrhoea as a symptom of enterocolitis
- Blood picture changes
- Herxheimer's reaction during spirochaetal infections treatment
- Transient discolouration of the teeth
- Potential for antibiotic-induced resistant microorganism proliferation
Pregnancy & Lactation
- Crosses the placenta
- Passes into the breast milk in small amounts
- Appropriate use during pregnancy and lactation
Precautions & Warnings
- Possibility of cross-allergy between cephalosporins and penicillins
- Consideration of the potassium content in patients with heart diseases or electrolyte disturbances
- Predisposition to encephalopathy risk
- Check patient's condition at regular intervals
- Consideration for sugar content in patients with diabetes mellitus
- No impairment of ability to drive or operate machinery
- Precautions in case of adverse reactions such as encephalopathy
Overdose Effects
- Low toxicity
- Broad therapeutic range
- Risk of encephalopathy in case of beta-lactam antibiotics administration
- No special measures required other than discontinuation of medication
- Possibility of elimination through haemodialysis
Therapeutic Class
- Benzylpenicillin
- Phenoxymethyl penicillin
Storage Conditions
- Cool and dry storage
- Protection from light