Pacet 200 mg (Tablet)
Unit Price: ৳ 10.05 (3 x 10: ৳ 301.35)
Strip Price: ৳ 100.45
Medicine Details
| Category | Details |
|---|---|
| Generic | Amiodarone hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title and Categories
- Pacet Tablet
- Pacet Injection
- Antiarrhythmic Medication
- Arrhythmia Treatment
- Medication for Heart Rhythms
- Amiodarone Hydrochloride
- Potassium Channel Blockers
Dimensions
Color Options
Functions
- Corrects abnormal rhythms of the heart
- Initiates and prophylaxes treatment for ventricular fibrillation and unstable ventricular tachycardia
- Delays heart's electrical system recharge
- Prolongs electrical phase in heart's muscle cells
- Reduces rapidity of firing of the heart's pacemaker
- Causes blood vessels to dilate
Materials
- Active ingredient: Amiodarone Hydrochloride
Technical Specifications
- Tablet: 200 mg, to be taken 3 times daily for 1 week, then reduced to 200 mg twice daily
- Injection: Starting dose of about 1000 mg over the first 24 hours
Design Elements
Usability Features
- Tablet should be taken with meals to minimize stomach upset
- Injection delivered by specific infusion regimen
Indications
- Used for serious arrhythmias of the heart including ventricular and atrial fibrillation/flutter
- Initiates treatment for frequently recurring ventricular fibrillation and unstable ventricular tachycardia
Pharmacology
- Amiodarone considered a 'broad spectrum' antiarrhythmic medication
Dosage & Administration
- Tablet: 200 mg 3 times daily for 1 week, reduced to 200 mg twice daily
- Injection: Specific infusion regimen over 24 hours
Interaction
- Interacts with b blockers, calcium channel blockers, digoxin, flecainide, procainamide, quinidine, tricyclic antidepressants, warfarin, and dextromethorphan
Contraindications
- Contraindicated in patients with cardiogenic shock, severe sinus-node dysfunction, atrioventricular block, marked sinus bradycardia, known hypersensitivity, or history of bradycardia-induced syncope
Side Effects
- Severe side effects related to the lungs; fatal liver toxicity; reversible corneal microdeposits; impaired vision; peripheral neuropathy and myopathy; bradycardia and conduction disturbances; phototoxicity and skin discoloration; hypothyroidism and hyperthyroidism; raised serum transaminases; jaundice, hepatitis, and cirrhosis; gastrointestinal complaints; neurological disorders; rashes; vasculitis; renal involvement; hematological abnormalities
- May require dose reduction or discontinuation of therapy
Pregnancy & Lactation
- Should not be administered during pregnancy due to risks of hypo or hyperthyroidism in infants
- Safe use during lactation not established
Therapeutic Class
- Potassium channel blockers
Storage Conditions
- Keep below 30°C temperature, away from light & moisture
- Keep out of the reach of children