Clox-F 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 60.00

Medicine Details

Indications

  • Treats skin and soft tissue infections
  • Treats respiratory tract infections
  • Effective against osteomyelitis, enteritis, endocarditis
  • Used as a prophylactic agent during major surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Inhibits cell wall formation of bacteria
  • Bactericidal against penicillinase-producing staphylococci

Dosage

  • Oral administration for adults: 250 mg four times daily
  • Dosage may be doubled in severe infections
  • Parenteral administration for adults: 250 mg-1 g four times daily
  • Oral doses should be administered 1 hour before a meal

Administration

Oral doses should be administered 1 hour before a meal

Interaction

Concurrent use may result in increased levels of Clox-F in blood

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea, vomiting, diarrhea, dyspepsia
  • Rashes, urticaria, purpura, fever
  • Interstitial nephritis, hepatitis, cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution during lactation
  • No adequate and well-controlled studies in pregnant women

Precautions & Warnings

  • Use with caution in patients with hepatic dysfunction
  • Caution in the treatment of patients with an allergic diathesis

Use in Special Populations

Consider dose reduction in severe renal failure

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

Administered in other routes in conjunction with systemic therapy

Storage Conditions

Keep in a dry place away from light and heat, keep out of the reach of children

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