Dolopen 500 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Flucloxacillin sodium |
| Company | Techno drugs ltd |
| Also available as |
Title
Dolopen Medicine
Categories
- Antibiotics
- Medication
- Pharmaceutical
Description
Dolopen is indicated for the treatment of infections due to Gram-positive organisms, including infections caused by penicillinase producing staphylococci. It is active against skin and soft tissue infections, respiratory tract infections, and other infections. The mode of action involves inhibiting the formation of the bacterial cell wall. It is available for oral and parenteral administration, with dosage recommendations for adults, children, and elderly patients. The oral administration should be taken 1 hour before a meal. Concurrent use of Dolopen and certain medications may result in increased levels of Dolopen in the blood. It is contraindicated in penicillin hypersensitive patients and should be used with caution in patients with evidence of hepatic dysfunction. The therapeutic class is penicillinase-resistant penicillins. Dolopen is categorized as US FDA Pregnancy Category B and caution should be exercised when administered to lactating mothers. It should be stored in a dry place away from light and heat, and out of the reach of children.
Dosage
- 250 mg four times daily for adults
- Doubled dosage in severe infections
- Dosage for children and elderly patients
- Intramuscular and intravenous injection recommendations
Administration
Oral doses should be administered 1 hour before a meal.
Interaction
Concurrent use of Dolopen and certain medications may result in increased level of Dolopen in blood for prolonged period.
Contraindications
Flucloxacillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Rashes
- Urticaria
- Purpura
- Fever
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
Pregnancy & Lactation
US FDA Pregnancy Category B. Caution should be exercised when used in lactating mothers.
Precautions & Warnings
Dolopen should be used with caution in patients with evidence of hepatic dysfunction and in the treatment of patients with an allergic diathesis.
Use in Special Populations
In severe renal failure, a reduction in dose or an extension of dose interval should be considered.
Therapeutic Class
Penicillinase-resistant penicillins
Reconstitution
Dolopen has been used in other routes in conjunction with systemic therapy.
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.