Fluclox DS 250 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 135.00

Medicine Details

Category Details
Generic Flucloxacillin sodium
Company Aci limited
Also available as
Fluclox 250 mg capsule Fluclox 500 mg capsule Fluclox 125 mg suspension Fluclox 250 mg injection Fluclox 500 mg injection

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infection
  • Meningitis
  • Septicaemia
  • Prophylactic agent for surgical procedures

Pharmacology

Active against Gram-positive organisms, penicillinase producing strains, little activity against Gram-negative bacilli, inhibits formation of bacteria cell wall, bactericidal antibiotic

Dosage

  • Oral administration:
    • Adult: 250 mg four times daily, up to 8 gm daily in severe infections
    • Children (2-10 years): half of adult dose
    • Children (Under 2 years): a quarter of adult dose
  • Parenteral administration:
    • Adult or Elderly:
      • Intramuscular Injection: 250 mg four times daily
      • Intravenous Injection: 250 mg-1 g four times daily, doses may be doubled in severe infections, doses up to 8 g daily for endocarditis or osteomyelitis
    • Children:
      • 2-10 years: half of adult dose
      • Under 2 years: a quarter of adult dose

Administration

Oral doses should be administered 1 hour before meal

Interaction

Concurrent use may result in increased level of Fluclox DS in blood for prolonged period

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Dyspepsia
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • Pregnancy Category: B
  • Cautions during lactation: Flucloxacillin excreted in human milk, caution should be exercised

Precautions & Warnings

Use with caution in patients with hepatic dysfunction, allergic diathesis

Use in Special Populations

Reduce dose or extend dose interval in severe renal failure

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

Used in other routes in conjunction with systemic therapy, administered by intraarticular and intrapleural injection, inhaled by nebuliser

Storage Conditions

Keep in dry place away from light and heat, keep out of reach of children

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