Fluclox 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 60.00

Medicine Details

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis treatment
  • Enteritis treatment
  • Endocarditis treatment
  • Urinary tract infection treatment
  • Meningitis treatment
  • Septicaemia treatment

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Inhibits formation of bacterial cell wall
  • Bactericidal antibiotic
  • Resistance to hydrolysis by penicillinase
  • Inhibits peptidoglycan synthesis
  • Mechanism of action against bacterial cell wall

Dosage

  • Oral administration
  • Adult dosage: 250 mg four times daily
  • Children dosage: 1/2 of adult dose (2-10 years)

Administration

  • Oral administration 1 hour before meal

Interaction

  • Concurrent use may increase Flucloxacillin levels in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common side effects: nausea, vomiting, diarrhea
  • Other reported side effects: rashes, urticaria, fever, hepatitis

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • No adequate and well-controlled studies in pregnant women
  • Excreted in human milk
  • Caution in lactating mothers

Precautions & Warnings

  • Caution in patients with hepatic dysfunction
  • Caution in patients with allergic diathesis

Use in Special Populations

  • Caution in severe renal failure patients

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Administered via intraarticular and intrapleural injection
  • Administered by nebulizer

Storage Conditions

  • Keep in dry place away from light and heat

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