Flupen 250 mg (Capsule)

Unit Price: ৳ 5.50 (10 x 7: ৳ 385.00)
Strip Price: ৳ 38.50

Medicine Details

Title and Category

  • Flucloxacillin Medicine Product

Primary Indication

  • Treatment of infections due to Gram-positive organisms
  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infection
  • Meningitis
  • Septicaemia

Pharmacology

  • Active against Gram-positive organisms
  • Inhibits the formation of bacterial cell wall
  • Little activity against Gram-negative bacilli
  • Bactericidal antibiotic
  • Useful against penicillinase-producing staphylococci
  • Interferes with peptidoglycan synthesis

Dosage

  • Oral administration
  • Dosage for adults and children
  • Parenteral administration
  • Intramuscular and intravenous injection
  • Dosage adjustments for severe infections

Administration

  • Oral doses to be administered 1 hour before meal

Interaction

  • Potential interaction with other medications resulting in increased levels in the blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common side effects like nausea, vomiting, diarrhea, dyspepsia
  • Minor gastrointestinal disturbances
  • Rashes, urticaria, purpura
  • Fever, interstitial nephritis, hepatitis, cholestatic jaundice

Pregnancy and Lactation

  • US FDA Pregnancy Category B
  • Caution during pregnancy and lactation

Precautions

  • Use with caution in patients with hepatic dysfunction
  • Caution in allergic diathesis

Use in Special Populations

  • Consider dose reduction in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes in conjunction with systemic therapy
  • Administered in intraarticular and intrapleural injections
  • Dissolved in sterile water and inhaled by nebulizer

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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