G-Flucloxacillin 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 25.00

Medicine Details

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infection
  • Meningitis
  • Septicaemia

Pharmacology

  • Active against Gram-positive organisms
  • Inhibits formation of cell wall of bacteria
  • Resistance to hydrolysis by penicillinase
  • Bactericidal antibiotic
  • Interferes with peptidoglycan synthesis

Dosage

  • Oral administration for adults
  • Oral administration for children (2-10 years)
  • Oral administration for children (Under 2 years)
  • Parenteral administration for adults or elderly
  • Parenteral administration for children (2-10 years)
  • Parenteral administration for children (Under 2 years)

Administration

  • Oral doses should be administered 1 hour before meal

Interaction

  • Concurrent use may result in increased level in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common side effects in gastrointestinal tract
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Excreted in human milk
  • Caution should be exercised when administered to lactating mother

Precautions & Warnings

  • Use with caution in patients with hepatic dysfunction
  • Caution in treatment of patients with allergic diathesis

Use in Special Populations

  • Reduction in dose in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Administered in other routes in conjunction with systemic therapy
  • Administered by intraarticular injection
  • Administered by intrapleural injection
  • Administered using powder for injection via nebuliser

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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