G-Flucloxacillin 125 mg/5 ml (Powder for Suspension)
100 ml bottle: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Flucloxacillin sodium |
| Company | Gonoshasthaya pharma ltd |
| Also available as |
Indications
- Treatment of Gram-positive infections
- Skin and soft tissue infections
- Respiratory tract infections
- Osteomyelitis treatment
- Endocarditis treatment
- Urinary tract infection treatment
- Meningitis treatment
- Septicaemia treatment
- Prophylactic agent for major surgical procedures
Pharmacology
- Active against Gram-positive organisms
- Little activity against Gram-negative bacilli
- Inhibits the formation of bacterial cell wall
- Bactericidal antibiotic
- Interferes with peptidoglycan synthesis
- Resistance to hydrolysis by penicillinase
- Gastric acid stability
- Mechanical stability of cell wall
Dosage
- Oral administration for adults
- Oral administration for children
- Parenteral administration for adults
- Parenteral administration for children
- Higher dosage in severe infections
- Dosage for osteomyelitis and endocarditis
Administration
- Oral administration 1 hour before meal
Interaction
- Concurrent use implications
Contraindications
- Contraindicated in penicillin hypersensitive patients
Side Effects
- Common gastrointestinal side effects
- Rashes
- Urticaria
- Purpura
- Fever
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Lack of adequate studies in pregnant women
- Potential excretion in human milk
- Caution during lactation
Precautions & Warnings
- Caution in hepatic dysfunction patients
- Caution in patients with allergic diathesis
Use in Special Populations
- Caution in severe renal failure
Therapeutic Class
- Penicillinase-resistant penicillins
Reconstitution
- Use in other routes in conjunction with systemic therapy
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children