Amdin 5 mg (Tablet)
Unit Price: ৳ 4.01 (5 x 10: ৳ 200.50)
Strip Price: ৳ 40.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Alco pharma ltd |
| Also available as |
Indications
- Hypertension
- Angina pectoris
- Vasospastic angina
- Monotherapy
- Combination therapy
Pharmacology
- Calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose 5 mg once daily
- Max dose 10 mg once daily
- Start dose for elderly patients with hepatic insufficiency 2.5 mg once daily
- Lower dose for chronic stable or vasospastic angina
- May be taken without regard to meals
Drug Interactions
- Potentially hazardous interactions with p-blockers in patients with markedly impaired cardiac left ventricular function
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration of Warfarin effect on prothrombin time
- No alteration by food on absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- No adequate and well-controlled studies
- Use during pregnancy only if potential benefit justifies potential risk to fetus
- Unknown excretion in human milk
- Discontinuation of nursing while administered
Precautions & Warnings
- Hepatic impairment
- Pregnancy
- Breastfeeding
Use in Special Populations
- Children with hypertension from 6 years to 17 years of age
- Starting dose for children 2.5 mg once daily
- Elderly patients
- Renal impairment
- Hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Systemic hypotension
- Shock with fatal outcome
- Active cardiovascular support required
- Frequent monitoring of cardiac and respiratory function
- Elevation of extremities
- Attention to circulating fluid volume and urine output
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in cool & dry place
- Protected from light