Phylopen DS 500 mg (Capsule)

Unit Price: ৳ 14.00 (7 x 6: ৳ 588.00)
Strip Price: ৳ 84.00

Medicine Details

Category Details
Generic Flucloxacillin sodium
Company Square pharmaceuticals plc
Also available as
Phylopen 250 mg capsule Phylopen 125 mg suspension Phylopen forte 250 mg suspension Phylopen 500 mg injection

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infection
  • Meningitis
  • Septicaemia
  • Prophylactic agent for major surgical procedures

Pharmacology

Active against Gram-positive organisms including penicillinase producing strains. Little activity against Gram-negative bacilli. Inhibits the formation of cell wall of bacteria. Bactericidal antibiotic. Useful against penicillinase-producing staphylococci.

Dosage

  • Oral administrationAdult: 250 mg four times daily, may be doubled in severe infections. Up to 8 gm daily in severe cases
  • Oral administrationChildren (2-10 years): 1/2 of adult dose
  • Oral administrationChildren (Under 2 years): 1/4 of adult dose
  • Parenteral administrationAdult or ElderlyIntramuscular Injection: 250 mg four times daily
  • Parenteral administrationAdult or ElderlyIntravenous Injection: 250 mg-1 g four times daily
  • Parenteral administrationChildren (2-10 years): half of the adult dose
  • Parenteral administrationChildren (Under 2 years): a quarter of the adult dose

Administration

Oral doses should be administered 1 hour before meal.

Interaction

Concurrent use with certain drugs may result in increased levels of Phylopen DS in blood for prolonged period.

Contraindications

Contraindicated in penicillin hypersensitive patients.

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Dyspepsia
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

US FDA Pregnancy Category B. Caution in use during lactation.

Precautions & Warnings

Use with caution in patients with hepatic dysfunction and allergic diathesis.

Use in Special Populations

In severe renal failure, consider a reduction in dose or an extension of dose interval.

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

Administered in other routes in conjunction with systemic therapy. Can be administered through intraarticular and intrapleural injection. Can be inhaled by nebuliser.

Storage Conditions

Store in a dry place away from light and heat. Keep out of the reach of children.

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