Phylopen 500 mg/vial (IM/IV Injection)

500 mg vial: ৳ 45.30 (5's pack: ৳ 226.50)

Medicine Details

Category	Details
Generic	Flucloxacillin sodium
Company	Square pharmaceuticals plc
Also available as	Phylopen 250 mg capsule Phylopen ds 500 mg capsule Phylopen 125 mg suspension Phylopen forte 250 mg suspension

Indications

Treatment of skin and soft tissue infections
Treatment of respiratory tract infections
Treatment of other infections like osteomyelitis, enteritis, endocarditis
Prophylactic use during major surgical procedures

Pharmacology

Active against Gram-positive organisms
Little activity against Gram-negative bacilli
Inhibits the formation of bacterial cell wall
Resistance to hydrolysis by penicillinase
Bactericidal antibiotic
Inhibits transpeptidase enzyme

Dosage

Oral administration for adults: 250 mg four times daily
Increased dosage for severe infections
Intramuscular and intravenous administration
Dosage adjustments for children

Administration

Oral doses to be administered 1 hour before a meal

Interaction

Concurrent use may increase Phylopen levels in blood

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

Gastrointestinal side effects such as nausea, vomiting, diarrhea
Rashes, urticaria, purpura
Interstitial nephritis, hepatitis, cholestatic jaundice

Pregnancy & Lactation

US FDA Pregnancy Category B
Use during pregnancy only if clearly needed
Caution during lactation

Precautions & Warnings

Caution in patients with hepatic dysfunction
Caution in patients with allergic diathesis

Use in Special Populations

Caution in severe renal failure

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

Used in other routes in conjunction with systemic therapy
Administered by intraarticular and intrapleural injection
Administered by inhalation using a nebulizer

Storage Conditions

Keep in a dry place away from light and heat
Keep out of the reach of children

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