S-Fluclox 250 mg (Capsule)

Unit Price: ৳ 7.00 (40's pack: ৳ 280.00)

Medicine Details

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis treatment
  • Enteritis treatment
  • Endocarditis treatment
  • Urinary tract infection treatment
  • Meningitis treatment
  • Septicaemia treatment
  • Prophylactic agent for surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Inhibits the formation of cell wall of bacteria
  • Resistance to hydrolysis by penicillinase
  • Gastric acid stability
  • Bactericidal antibiotic
  • Useful against penicillinase-producing staphylococci

Dosage

  • Oral administration for adults: 250 mg four times daily
  • Oral administration for children (2-10 years): 1/2 of adult dose
  • Oral administration for children (under 2 years): 1/4 of adult dose
  • Parenteral administration for adults: 250 mg four times daily
  • Slow intravenous injection over 3 to 4 minutes

Administration

  • Oral doses should be administered 1 hour before meal

Interaction

  • Concurrent use may result in increased level of S-Fluclox in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Gastrointestinal side effects such as nausea, vomiting, diarrhea
  • Rashes, urticaria, purpura
  • Fever, interstitial nephritis, hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution should be exercised when administered to a lactating mother

Precautions & Warnings

  • Use with caution in patients with hepatic dysfunction
  • Use with caution in patients with an allergic diathesis

Use in Special Populations

  • In severe renal failure, consider reduction in dose or extension of dose interval

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes in conjunction with systemic therapy
  • Administered by intraarticular injection

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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