Silox 500 mg (Capsule)

Unit Price: ৳ 10.04 (5 x 4: ৳ 200.80)
Strip Price: ৳ 40.16

Medicine Details

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Urinary tract infection
  • Meningitis
  • Septicaemia

Pharmacology

  • Active against Gram-positive organisms
  • Inhibits the formation of cell wall of bacteria
  • Bactericidal antibiotic
  • Resistance to hydrolysis by penicillinase
  • Weakens bacterial cell wall

Dosage

  • Oral administration for adults, children, and parenteral administration
  • Dosage may be doubled in severe infections
  • Up to 8 gm daily used in severe cases

Administration

Oral doses should be administered 1 hour before meal

Interaction

Concurrent use may result in increased level of Silox in blood for prolonged period

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Rashes
  • Fever
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution should be exercised when administered to a lactating mother

Precautions & Warnings

  • Use with caution in patients with evidence of hepatic dysfunction
  • Caution in patients with allergic diathesis

Use in Special Populations

In severe renal failure, a reduction in dose or an extension of dose interval should be considered

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes in conjunction with systemic therapy
  • Administered by intraarticular injection
  • Inhaled by nebuliser four times daily

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children

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