Amdoper 5 mg (Tablet)
Unit Price: ৳ 3.00 (30's pack: ৳ 90.00)
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate |
Company | Hallmark pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vascular smooth muscle
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Maximum dose is 10 mg once daily
- Lower dose for elderly and hepatic insufficiency
- 5 to 10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Rashes
- Fever
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy if potential benefit justifies risk to fetus
- Discontinue nursing while administered
Precautions & Warnings
- Hepatic impairment
- Pregnancy
- Breastfeeding
Use in Special Populations
- Dosage for children with hypertension
- Elderly tolerance
- Renal impairment
- Hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Systemic hypotension
- Shock
- Active cardiovascular support needed
- Elevation of extremities
- Attention to fluid volume and urine output
- Vasoconstrictor may be beneficial
- Intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile
- Use of charcoal shown to reduce absorption rate
- Dialysis unlikely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in cool & dry place
- Protected from light