Amdoper 5 mg (Tablet)

Unit Price: ৳ 3.00 (30's pack: ৳ 90.00)

Medicine Details

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Pharmacology

  • Dihydropyridine calcium-channel blocker
  • Long duration of action
  • Influences myocardial cells
  • Vascular smooth muscle
  • Vasodilation
  • Reduced peripheral resistance
  • Increased coronary blood flow

Dosage & Administration

  • Usual dose is 5 mg once daily for hypertension
  • Maximum dose is 10 mg once daily
  • Lower dose for elderly and hepatic insufficiency
  • 5 to 10 mg for angina
  • May be taken without regard to meals

Interaction

  • Potentially hazardous interactions with p-blockers
  • No interaction with Digoxin
  • No interaction with Cimetidine
  • No significant alteration with Warfarin
  • Food does not alter absorption

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnant women

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Gastrointestinal disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Rashes
  • Fever

Pregnancy & Lactation

  • Pregnancy Category C
  • Use during pregnancy if potential benefit justifies risk to fetus
  • Discontinue nursing while administered

Precautions & Warnings

  • Hepatic impairment
  • Pregnancy
  • Breastfeeding

Use in Special Populations

  • Dosage for children with hypertension
  • Elderly tolerance
  • Renal impairment
  • Hepatic impairment

Overdose Effects

  • Excessive peripheral vasodilatation
  • Reflex tachycardia
  • Systemic hypotension
  • Shock
  • Active cardiovascular support needed
  • Elevation of extremities
  • Attention to fluid volume and urine output
  • Vasoconstrictor may be beneficial
  • Intravenous calcium gluconate may be beneficial
  • Gastric lavage may be worthwhile
  • Use of charcoal shown to reduce absorption rate
  • Dialysis unlikely to be beneficial

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Keep out of reach of children
  • Store in cool & dry place
  • Protected from light

Related Brands