Skilox 250 mg (Capsule)

Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00

Medicine Details

Indications

  • Treatment of skin and soft tissue infections
  • Treatment of respiratory tract infections
  • Treatment of osteomyelitis
  • Treatment of endocarditis
  • Prophylactic use during surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Resistance to hydrolysis by penicillinase
  • Bactericidal antibiotic
  • Inhibition of peptidoglycan synthesis
  • Weakens bacterial cell wall

Dosage

  • Oral administration:
    • Adult: 250 mg four times daily
    • Children (2-10 years): 1/2 of adult dose
    • Children (Under 2 years): 1/4 of adult dose
  • Parenteral administration:
    • Adult: Intramuscular Injection: 250 mg four times daily, Intravenous Injection: 250 mg-1 g four times daily
    • Children:
      • 2-10 years: half of the adult dose
      • Under 2 years: a quarter of the adult dose

Administration

Oral doses should be administered 1 hour before a meal

Interaction

Concurrent use may result in increased levels of the medicine in the blood for a prolonged period

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Rashes
  • Urticaria
  • Fever
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

Pregnancy Category B, caution advised during lactation

Precautions & Warnings

  • Use with caution in patients with evidence of hepatic dysfunction
  • Caution in patients with an allergic diathesis

Use in Special Populations

Consider dosage adjustment in severe renal failure

Therapeutic Class

Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes in conjunction with systemic therapy
  • Administered by intraarticular and intrapleural injection
  • Administered by nebulizer

Storage Conditions

Keep in a dry place, away from light and heat. Keep out of the reach of children

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