Sofa 250 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Flucloxacillin sodium |
| Company | Apollo pharmaceutical ltd |
| Also available as |
Title
Sofa Medicine
Categories
- Antibiotic
- Medication
- Pharmaceutical
Description
Sofa is indicated for the treatment of infections due to Gram-positive organisms, including infections caused by penicillinase producing staphylococci. It is used for treating skin and soft tissue infections, respiratory tract infections, osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia, and as a prophylactic agent during major surgical procedures. Flucloxacillin is active against Gram-positive organisms including penicillinase producing strains. It has little activity against Gram-negative bacilli. Oral and parenteral administration are available. The medicine should be administered 1 hour before a meal. Concurrent use with specific medications may result in increased levels of Sofa in the blood. It is contraindicated in penicillin hypersensitive patients. Common side effects include gastrointestinal disturbances, rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis, and cholestatic jaundice. The US FDA Pregnancy Category of Flucloxacillin is B, caution should be exercised when administered to a lactating mother.
Dimensions
N/A
Color Options
N/A
Functions
- Treat infections
- Bactericidal
- Prophylactic use
- Inhibits formation of bacterial cell wall
- Kills bacterial cell wall
Materials
- Flucloxacillin
Technical Specifications
- Oral Administration:
- Adult: 250 mg four times daily
- Children (2-10 years): 1/2 of adult dose
- Children (Under 2 years): 1/4 of adult dose
- Parenteral Administration:
- Adult or Elderly:
- Intramuscular Injection: 250 mg four times daily
- Intravenous Injection: 250 mg-1 g four times daily
- Children:
- 2-10 years: Half of the adult dose
- Under 2 years: A quarter of the adult dose
- Adult or Elderly:
Design Elements
N/A
Usability Features
Should be administered 1 hour before meal
Interaction
Concurrent use of Sofa with specific medications may result in increased level of Sofa in blood for prolonged period.
Contraindications
Flucloxacillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Dyspepsia
- Rashes
- Urticaria
- Purpura
- Fever
- Interstitial nephritis
- Hepatitis
- Cholestatic jaundice
Pregnancy & Lactation
US FDA Pregnancy Category of Flucloxacillin is B. Caution should be exercised when administered to a lactating mother.
Precautions & Warnings
Sofa should be used with caution in patients with evidence of hepatic dysfunction. Caution should also be exercised in the treatment of patients with an allergic diathesis.
Use in Special Populations
In severe renal failure, a reduction in dose or an extension of dose interval should be considered.
Therapeutic Class
Penicillinase-resistant penicillins
Reconstitution
Sofa has been used in other routes in conjunction with systemic therapy. It has been administered in a dose of 250 mg to 500 mg daily by intraarticular injection, dissolved if necessary in a 0.5% solution of lignocaine hydrochloride, and by intrapleural injection in a dose of 250 mg daily. Using powder for injection, 125 mg-250 mg has been dissolved in 3 ml of sterile water and inhaled by nebuliser four times daily.
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.