Amlo 5 mg (Tablet)
Unit Price: ৳ 3.50 (50's pack: ৳ 175.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Pharmadesh laboratories ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vasodilation
- Increased coronary blood flow
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Maximum dose is 10 mg once daily for hypertension
- 5 to 10 mg for angina
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers in patients with impaired cardiac left ventricular function
- No interaction between Amlo and Digoxin
- No interaction between Amlo and Cimetidine
- No significant alteration of Warfarin effect by Amlo
- Food does not alter absorption of Amlo
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant woman
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Paradoxical increase in ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if potential benefit justifies potential risk to fetus
- Recommendation to discontinue nursing while Amlodipine is administered
Precautions & Warnings
- Precaution in patients with hepatic impairment
- Precaution during pregnancy and breastfeeding
Use in Special Populations
- Dosage recommendations for children with hypertension
- Effect on blood pressure in patients less than 6 years of age not known
- Normal dosage regimens recommended in the elderly
- Normal dosage recommended in renal impairment
- Dosage recommendations not established in patients with mild to moderate hepatic impairment
- Initiate at lowest dose in patients with severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and probably prolonged systemic hypotension
- Active cardiovascular support required
- Vasoconstrictor may be helpful
- Intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile
- Use of charcoal shown to reduce absorption rate of amlodipine
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep all medicines out of reach of children
- Store in a cool & dry place, protected from light