Staphylox-500 500 mg (Capsule)

Unit Price: ৳ 10.50 (28's pack: ৳ 294.00)

Medicine Details

Title

  • Staphylox-500

Categories

  • Medicine
  • Pharmaceuticals

Description

  • An antibiotic indicated for the treatment of infections caused by Gram-positive organisms, including penicillinase-producing staphylococci.

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis
  • Enteritis
  • Endocarditis
  • Urinary tract infection
  • Meningitis
  • Septicaemia
  • Prophylactic agent for major surgical procedures

Mode of Action

  • Acts by inhibiting the formation of bacteria cell wall
  • Bactericidal antibiotic
  • Resistant to hydrolysis by penicillinase

Dosage

  • Oral administration for adults: 250 mg four times daily
  • Parenteral administration for adults: 250 mg four times daily
  • Dosage may be doubled in severe infections

Administration

  • Oral doses should be administered 1 hour before a meal

Interaction

  • Concurrent use may result in increased levels of Staphylox-500 in blood for a prolonged period

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Rashes
  • Urticaria
  • Purpura
  • Fever
  • Interstitial nephritis
  • Hepatitis
  • Cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Excreted in human milk
  • Caution advised during lactation and pregnancy if clearly needed

Precautions & Warnings

  • Use with caution in patients with evidence of hepatic dysfunction

Use in Special Populations

  • Caution in severe renal failure (creatinine clearance <10 ml/min)

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Administered in other routes in conjunction with systemic therapy
  • Intraarticular and intrapleural injection options available

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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