Syflu 500 mg (Capsule)
Unit Price: ৳ 10.00 (30's pack: ৳ 300.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Flucloxacillin sodium |
| Company | Mst pharma |
| Also available as |
Indications
- Treatment of skin and soft tissue infections
- Treatment of respiratory tract infections
- Treatment of osteomyelitis
- Prophylactic use during major surgical procedures
Pharmacology
- Active against Gram-positive organisms
- Inhibits the formation of bacterial cell wall
- Resistance to hydrolysis by penicillinase
- Bactericidal antibiotic
- Interferes with peptidoglycan synthesis
Dosage
- Oral administration for adults: 250 mg four times daily
- Oral administration for children (2-10 years): Half of adult dose
- Parenteral administration for adults: 250 mg-1 g four times daily
- Parenteral administration for children (2-10 years): Half of adult dose
Administration
- Oral doses should be administered 1 hour before a meal
Interaction
- Concurrent use may result in increased levels of Syflu in the blood for a prolonged period
Contraindications
- Contraindicated in penicillin hypersensitive patients
Side Effects
- Common gastrointestinal side effects: Nausea, vomiting, diarrhea, dyspepsia
- Other reported side effects: Rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis, cholestatic jaundice
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Caution should be exercised when administered to a lactating mother
Precautions & Warnings
- Use with caution in patients with evidence of hepatic dysfunction
- Caution in the treatment of patients with an allergic diathesis
Use in Special Populations
- Consider dose reduction in severe renal failure (creatinine clearance <10 ml/min)
Therapeutic Class
- Penicillinase-resistant penicillins
Reconstitution
- Administered in other routes in conjunction with systemic therapy
- Dissolved if necessary in a 0.5% solution of lignocaine hydrochloride for intraarticular injection
- Dissolved in sterile water and inhaled by nebulizer four times daily
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children