Seemacillin 125 mg/1.25 ml (Pediatric Drops)

15 ml drop: ৳ 17.65

Medicine Details

Indications

  • Genitourinary tract infections
  • Respiratory tract infections
  • Gastrointestinal tract infections
  • Meningitis
  • Bacteriology studies
  • Susceptibility testing

Pharmacology

  • Inhibition of bacterial cell wall synthesis
  • Binding to penicillin-binding proteins
  • Inhibition of transpeptidation step
  • Lysis of bacteria
  • Activity of cell wall autolytic enzymes

Dosage

  • Intra-articular administration
  • Intraperitoneal administration
  • Intrapleural administration
  • Intravenous administration
  • Oral administration
  • Parenteral administration
  • Septicaemia treatment
  • Intrapartum prophylaxis
  • Dosage for adults and children
  • Dosage for specific infections
  • Dosage adjustments for renal impairment

Administration

  • Administration on an empty stomach
  • Timing of administration in relation to meals

Interactions

  • Effect on oral contraceptives
  • Effects on INR with warfarin and phenindione
  • Effect on oral typhoid vaccines
  • Effect on excretion of methotrexate
  • Interactions with probenecid and sulfinpyrazone
  • Interactions with allopurinol
  • Reduced absorption with chloroquine
  • Interference with bactericidal action of other antibiotics

Contraindications

  • Hypersensitivity to penicillins

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Rash
  • Stevens-Johnson syndrome
  • Haemolytic anaemia
  • Thrombocytopenia
  • Leucopenia
  • Neutropenia
  • CNS toxicity
  • Nephropathy
  • Hepatitis
  • Cholestatic jaundice
  • Anaphylaxis
  • Clostridium difficile-associated diarrhoea

Pregnancy & Lactation

  • Pregnancy Category B
  • Limited studies in pregnant women

Precautions & Warnings

  • β-lactam allergy
  • Renal impairment
  • Pregnancy and lactation

Use in Special Populations

  • Dose adjustments for renal impairment

Overdose Effects

  • Symptoms of overdose
  • Management of overdose

Reconstitution

  • Instructions for reconstitution
  • Reconstitution for different administration routes

Storage Conditions

  • Temperature for storage
  • Storage of reconstituted oral suspension

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