Amocil 500 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Mst pharma |
| Also available as |
Title
Amocil 500mg Capsule
Categories
- Medicine
- Antibiotic
- Pharmaceutical
Description
Amocil is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. These infections include various types of ear, nose and throat infections, lower respiratory tract infections, skin and soft tissue infections, genito-urinary tract infections, venereal disease, dental abscess, H. pylori infection, and duodenal ulcer disease. It is a broad spectrum penicillin, effective against a wide range of Gram-positive and Gram-negative bacteria. The recommended dosage for adults is 250-500 mg three times daily, while for children it is 125-250 mg three times daily. The reconstituted suspension can be administered by adding it to milk, fruit juice, or water. It is contraindicated in penicillin hypersensitive patients and may have side effects such as diarrhoea, indigestion, or rash. Amoxicillin has a US FDA pregnancy category of B and caution should be exercised when administered to lactating mothers. It belongs to the therapeutic class of broad spectrum penicillins and should be stored in a dry place away from light and heat.
Attributes
- Indications:
- Ear, Nose and Throat Infections
- Lower Respiratory Tract Infections
- Skin and Soft Tissue Infections
- Genito-urinary Tract Infections
- Venereal Disease
- Dental Abscess
- H. pylori Infection
- Duodenal Ulcer Disease
- Pharmacology: Broad Spectrum Penicillin, Inhibition of Cell Wall Biosynthesis, Rapid Absorption After Oral Administration, Wide Distribution in Body Tissues and Fluids
- Dosage:
- Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
- Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
- Severe Purulent Respiratory Infection: 3 gm every 12 hours
- Otitis Media: 1 g three times daily for adults, 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental Abscess: 3 gm, repeated after 10-12 hours
- Urinary Tract Infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm (Probenecid contraindicated in children under 2 years)
- Renal Impairment: May require reducing total daily dosage
- Administration: Reconstituted suspension can be administered by adding to milk, fruit juice, or water
- Interaction:
- Concurrent use with Probenecid may increase and prolong blood levels of Amocil
- May affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives
- Contraindications: Penicillin Hypersensitivity
- Side Effects:
- Diarrhoea
- Indigestion
- Rash
- Rarely Pseudo-membranous Colitis
- Pregnancy & Lactation: US FDA pregnancy category B, Excreted in human milk, Caution in lactating mothers
- Precautions & Warnings: Possibility of superinfections with mycotic or bacterial pathogens, appropriate therapy should be instituted if superinfections occur
- Therapeutic Class: Broad Spectrum Penicillins
- Reconstitution:
- Amoxycillin 500 mg Injection:
- Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
- Intravenous: Dissolve in 10 ml water for injection
- Amoxycillin 500 mg Injection:
- Storage Conditions: Keep in a dry place away from light and heat, Keep out of the reach of children