Amlocard 10 mg (Tablet)
Unit Price: ৳ 7.05 (4 x 14: ৳ 394.80)
Strip Price: ৳ 98.70
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate |
Company | Drug international ltd |
Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Reflex increase in coronary heart rate
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Maximum dose is 10 mg once daily for hypertension
- 5 to 10 mg for angina
- Can be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction between Amlocard and Digoxin
- No interaction between Amlocard and Cimetidine
- Amlocard did not significantly alter the effect of Warfarin on prothrombin time
- Food does not alter the rate or extent of absorption of Amlocard
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnant women
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
- Recommended to discontinue nursing while Amlodipine is administered
Precautions & Warnings
- Precautions in patients with hepatic impairment, pregnancy, and breastfeeding
Use in Special Populations
- Specific dosages for children of different age groups
- Elderly patients are well tolerated at normal dosage regimens
- Normal dosage recommended for patients with renal impairment
- Caution in dose selection for patients with hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked and prolonged systemic hypotension
- Clinically significant hypotension calls for active cardiovascular support
- Intravenous calcium gluconate may be beneficial in reversing the effects of calcium channel blockade
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light