Amlocard 10 mg (Tablet)

Unit Price: ৳ 7.05 (4 x 14: ৳ 394.80)
Strip Price: ৳ 98.70

Medicine Details

Category Details
Generic Amlodipine besilate
Company Drug international ltd
Also available as

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Pharmacology

  • Dihydropyridine calcium-channel blocker
  • Long duration of action
  • Vasodilation
  • Reduced peripheral resistance
  • Increased coronary blood flow
  • Reflex increase in coronary heart rate

Dosage & Administration

  • Usual dose is 5 mg once daily for hypertension
  • Maximum dose is 10 mg once daily for hypertension
  • 5 to 10 mg for angina
  • Can be taken without regard to meals

Interaction

  • Potentially hazardous interactions with p-blockers
  • No interaction between Amlocard and Digoxin
  • No interaction between Amlocard and Cimetidine
  • Amlocard did not significantly alter the effect of Warfarin on prothrombin time
  • Food does not alter the rate or extent of absorption of Amlocard

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnant women

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Ischaemic chest pain
  • Rashes
  • Fever
  • Abnormalities in liver function

Pregnancy & Lactation

  • Pregnancy Category C
  • Use during pregnancy only if potential benefit justifies potential risk to the fetus
  • Recommended to discontinue nursing while Amlodipine is administered

Precautions & Warnings

  • Precautions in patients with hepatic impairment, pregnancy, and breastfeeding

Use in Special Populations

  • Specific dosages for children of different age groups
  • Elderly patients are well tolerated at normal dosage regimens
  • Normal dosage recommended for patients with renal impairment
  • Caution in dose selection for patients with hepatic impairment

Overdose Effects

  • Excessive peripheral vasodilatation
  • Reflex tachycardia
  • Marked and prolonged systemic hypotension
  • Clinically significant hypotension calls for active cardiovascular support
  • Intravenous calcium gluconate may be beneficial in reversing the effects of calcium channel blockade

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Keep out of reach of children
  • Store in a cool & dry place
  • Protected from light

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