Amotid 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 70.00

Medicine Details

Indications

  • Treatment of infections due to susceptible -lactamase negative strains of microorganisms
  • Ear, nose and throat infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess therapy
  • Treatment of H. pylori infection and duodenal ulcer disease

Pharmacology

  • Broad spectrum penicillin
  • Effective against Gram-positive and Gram-negative bacteria
  • Inhibition of biosynthesis of cell wall
  • Stable in the presence of gastric acid
  • Rapidly absorbed after oral administration
  • Peak plasma concentration reached within 1 to 2 hours
  • Widely distributed in body tissues and fluids

Dosage

  • Adult dosage: 250 mg three times daily
  • Increased dosage for severe infections
  • Children dosage: 125 mg three times daily
  • Recommended dosages for specific infections such as otitis media, pneumonia, and dental abscess
  • Dosage adjustment in renal impairment

Administration

  • Reconstituted suspension can be administered by adding to milk, fruit juice, or water
  • Preparations should be taken immediately

Interaction

  • Concurrent use with Probenecid may increase and prolong blood levels
  • May affect gut flora, leading to lower estrogen reabsorption

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Mild and transient side effects
  • Potential side effects such as diarrhoea, indigestion, rash, and rarely, pseudo-membranous colitis

Pregnancy & Lactation

  • US FDA pregnancy category B
  • Caution advised during pregnancy and lactation

Precautions & Warnings

  • Possibility of superinfections with mycotic or bacterial pathogens should be kept in mind
  • Appropriate therapy should be instituted if superinfections occur

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • Reconstitution process for Amoxycillin 500 mg Injection

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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