Amoxima 500 mg (Capsule)

Unit Price: ৳ 6.65 (50's pack: ৳ 332.50)

Medicine Details

Category Details
Generic Amoxicillin trihydrate
Company Modern pharmaceuticals ltd
Also available as
Amoxima 125 mg suspension

Title

Amoxima

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

Amoxima is indicated in the treatment of a wide range of bacterial infections. It is a broad spectrum penicillin that acts through the inhibition of cell wall biosynthesis.

Indications

  • Ear, nose, and throat infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess
  • H. pylori infection
  • Duodenal ulcer disease

Pharmacology

Amoxicillin is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria. It is stable in the presence of gastric acid and rapidly absorbed after oral administration.

Dosage adult

250 mg three times daily, increasing up to 500 mg three times daily for severe infections

Dosage children

125 mg three times daily, increasing up to 250 mg three times daily for severe infections

Dosage additional recommendations

  • 3 gm every 12 hours for severe or recurrent purulent respiratory infection
  • 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children with otitis media
  • 500-1000 mg three times daily for pneumonia
  • 3 gm dose for dental abscess and urinary tract infections
  • 2-3 gm single dose with Probenecid for gonorrhea

Administration

Reconstituted suspension can be administered by adding the required amount to milk, fruit juice, or water.

Interaction

Concurrent use with Probenecid may result in increased and prolonged blood levels of Amoxima. Amoxima may affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral contraceptives.

Contraindications

Amoxicillin is contraindicated in penicillin hypersensitive patients.

Side effects

  • Diarrhea
  • Indigestion
  • Rash
  • Rarely pseudo-membranous colitis

Pregnancy lactation

US FDA pregnancy category B, caution should be exercised when administered to lactating mothers.

Precautions warnings

Possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy.

Therapeutic class

Broad spectrum penicillins

Reconstitution

  • Amoxycillin 500mg Injection:
    • Intramuscular: Add 2.5 ml water for injection to the vial
    • Intravenous: Dissolve in 10 ml water for injection

Storage conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

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