Amoxon 125 mg/5 ml (Powder for Suspension)
Medicine Details
Category | Details |
---|---|
Generic | Amoxicillin trihydrate |
Company | Jayson pharmaceuticals ltd |
Also available as |
Title
- Amoxon 500 mg
Categories
- Medicine
- Antibiotic
- Pharmaceutical
Description
Amoxon is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms, including ear, nose and throat infections, lower respiratory tract infections, skin and soft tissue infections, genito-urinary tract infections, venereal disease, dental abscess, and in combination therapy for H. pylori infection and duodenal ulcer disease.
Dosage
- Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
- Children (up to 10 years of age): 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
RecommendedDoses
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media: 1 g three times daily for adults, 40 mg/kg daily in 3 divided doses for children (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental abscess: 3 gm, repeated after 10-12 hours
- Urinary tract infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm (Probenecid contraindicated in children under 2 years)
- In renal impairment: Total daily dosage may need reduction
Pharmacology
Broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria, acts through the inhibition of cell wall biosynthesis, stable in the presence of gastric acid, rapidly absorbed after oral administration, widely distributed in body tissues and fluids
Administration
Reconstituted suspension can be administered by adding the required amount to milk, fruit juice, or water, and should be taken immediately
Interaction
Concurrent use with Probenecid may result in increased and prolonged blood levels, may affect gut flora leading to reduced efficacy of combined oral contraceptives
Contraindications
Contraindicated in penicillin hypersensitive patients
SideEffects
- Mild and transient, including diarrhoea, indigestion, occasionally rash, and rarely, pseudo-membranous colitis
PregnancyAndLactation
FDA category B, caution advised during pregnancy and lactation due to excretion in human milk
PrecautionsAndWarnings
Superinfections with mycotic or bacterial pathogens possible, discontinue if superinfections occur
TherapeuticClass
Broad spectrum penicillins
Reconstitution
For Amoxycillin 500 mg Injection: Intramuscular - Add 2.5 ml water for injection, Intravenous - Dissolve in 10 ml water for injection
StorageConditions
Keep in a dry place away from light and heat, keep out of reach of children