Amlopin 10 mg (Tablet)

Unit Price: ৳ 7.02 (3 x 10: ৳ 210.60)
Strip Price: ৳ 70.20

Medicine Details

Category Details
Generic Amlodipine besilate
Company Acme laboratories ltd
Also available as

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Pharmacology

  • Calcium-channel blocker
  • Long duration of action
  • Vasodilation
  • Reduced peripheral resistance
  • Increased coronary blood flow

Dosage & Administration

  • Usual dose 5 mg once daily for hypertension
  • Maximum dose 10 mg once daily for hypertension
  • 5 to 10 mg dose for angina pectoris
  • May be taken without regard to meals

Interaction

  • Potentially hazardous interactions with p-blockers in patients with impaired cardiac left ventricular function
  • No interaction between Amlopin and Digoxin
  • No interaction between Amlopin and Cimetidine
  • No significant alteration of Warfarin effect by Amlopin
  • Food does not alter absorption of Amlopin

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnancy

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema
  • Gastrointestinal disturbances
  • Increased micturition frequency
  • Lethargy
  • Eye pain
  • Mental depression
  • Rashes
  • Fever
  • Abnormalities in liver function

Pregnancy & Lactation

  • Pregnancy Category C
  • Use during pregnancy only if benefit justifies potential risk to fetus
  • Recommendation to discontinue nursing while Amlodipine is administered

Precautions & Warnings

  • Precaution in patients with hepatic impairment
  • Precaution during pregnancy and breastfeeding

Use in Special Populations

  • Specific dosing for children with hypertension from 6 to 17 years of age
  • Effect on blood pressure in children under 6 years not known
  • Normal dosage regimens recommended for elderly and patients with renal impairment
  • Caution and lower starting dose for patients with mild to moderate hepatic impairment
  • No established dosage recommendations for severe hepatic impairment

Overdose Effects

  • Excessive peripheral vasodilatation
  • Reflex tachycardia
  • Marked and probably prolonged systemic hypotension
  • Active cardiovascular support required
  • Gastric lavage may be worthwhile
  • Intravenous calcium gluconate may be beneficial

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Keep out of reach of children
  • Store in a cool & dry place, protected from light

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