Apimox 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 38.44

Medicine Details

Indications

  • Treatment of infections in ear, nose, and throat
  • Treatment of lower respiratory tract infections
  • Treatment of skin and soft tissue infections
  • Treatment of genito-urinary tract infections
  • Treatment of venereal diseases
  • Short-term therapy for dental abscess

Pharmacology

  • Amoxicillin is a broad spectrum penicillin
  • Effective against a wide range of bacteria
  • Acts through the inhibition of cell wall biosynthesis
  • Stable in gastric acid
  • Rapidly absorbed after oral administration

Dosage

  • Adult dosage: 250 mg three times daily
  • Severe adult dosage: up to 500 mg three times daily
  • Children dosage: 125 mg three times daily
  • Severe or recurrent purulent respiratory infection dosage: 3 gm every 12 hours
  • Otitis media dosage: 1 g three times daily for adults
  • Pneumonia dosage: 500-1000 mg three times daily
  • Dental abscess dosage: 3 gm, repeated after 10-12 hours
  • Urinary tract infections dosage: 3 gm, repeated after 10-12 hours

Administration

  • Reconstituted suspension can be administered by adding to milk, fruit juice, or water
  • Suspension should be taken immediately after preparation

Interaction

  • Concurrent use with probenecid may increase and prolong blood levels
  • May affect gut flora leading to lower estrogen reabsorption

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Mild and transient side effects
  • May include diarrhea, indigestion, rash
  • Rare cases of pseudo-membranous colitis reported

Pregnancy & Lactation

  • FDA pregnancy category B
  • Caution needed during pregnancy and lactation

Precautions & Warnings

  • Watch for superinfections with mycotic or bacterial pathogens
  • Discontinue if superinfections occur

Therapeutic Class

  • Broad spectrum penicillins

Reconstitution

  • For Amoxicillin 500 mg Injection
  • Intramuscular reconstitution: Add 2.5 ml water for injection
  • Intravenous reconstitution: Dissolve in 10 ml water for injection

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of reach of children

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