Apoxy 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 70.00

Medicine Details

Category Details
Generic Amoxicillin trihydrate
Company Apex pharmaceuticals ltd
Also available as

Indications

  • Ear, nose and throat infections
  • Lower respiratory tract infections
  • Skin and soft tissue infections
  • Genito-urinary tract infections
  • Venereal disease
  • Dental abscess

Pharmacology

Broad spectrum penicillin effective against a wide range of bacteria

Dosage

  • Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
  • Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
  • Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
  • Otitis media (Adult): 1 g three times daily
  • Otitis media (Children): 40 mg/kg body weight daily in 3 divided doses (max. 3 g daily)
  • Pneumonia: 500-1000 mg three times daily
  • Dental abscess: 3 gm, repeated after 10-12 hours
  • Urinary tract infections: 3 gm, repeated after 10-12 hours
  • Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm
  • Renal impairment: May require reduction of total daily dosage

Administration

Reconstituted suspension can be administered by adding to milk, fruit juice, or water

Interaction

  • Concurrent use with Probenecid may increase and prolong blood levels
  • May affect gut flora and reduce efficacy of combined oral contraceptives

Contraindications

Contraindicated in penicillin hypersensitive patients

Side Effects

  • Diarrhoea
  • Indigestion
  • Rash
  • Rarely pseudo-membranous colitis

Pregnancy & Lactation

  • Pregnancy Category: B
  • Recommendation: Use during pregnancy only if clearly needed, caution during lactation

Precautions & Warnings

Possibility of superinfections with mycotic or bacterial pathogens should be considered

Therapeutic Class

Broad spectrum penicillins

Reconstitution

  • Amoxycillin 500 mg Injection (Intramuscular): Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
  • Amoxycillin 500 mg Injection (Intravenous): Dissolve in 10 ml water for injection

Storage Conditions

Keep in a dry place away from light and heat, keep out of the reach of children

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