Avlomox 500 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Aci limited |
| Also available as |
Indications
- Ear, nose and throat infections
- Lower respiratory tract infections
- Skin and soft tissue infections
- Genito-urinary tract infections
- Venereal disease
- H. pylori infection
- Duodenal ulcer disease
Pharmacology
Amoxicillin is a broad spectrum penicillin, effective against a wide range of bacteria by inhibiting cell wall biosynthesis, and is stable in gastric acid.
Dosage
- Adult: 250 mg three times daily, increasing to 500 mg three times daily for severe infections
- Children: 125 mg three times daily, increasing to 250 mg three times daily for severe infections
- Specific doses:
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media: 1 g three times daily for adults, 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily)
- Pneumonia: 500-1000 mg three times daily
- Dental abscess: 3 gm, repeated after 10-12 hours
- Urinary tract infections: 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm (Probenecid is contraindicated in children under 2 years)
- Renal impairment: Total daily dosage reduction may be necessary
Administration
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, or water, and should be taken immediately.
Interaction
- Concurrent use of Avlomox and Probenecid may increase and prolong blood levels of Avlomox
- Avlomox may affect gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects
- Mild and transient side effects such as diarrhea, indigestion, occasionally rash
- Rarely reported pseudo-membranous colitis
Pregnancy & Lactation
Amoxicillin is US FDA pregnancy category B, caution should be exercised when administered to a lactating mother.
Precautions & Warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Avlomox should be discontinued and appropriate therapy should be instituted.
Therapeutic Class
Broad spectrum penicillins
Reconstitution
- Amoxycillin 500 mg Injection:
- Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial
- Intravenous: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection
Storage Conditions
Keep in a dry place away from light and heat, and out of the reach of children.